Prostate cancer prevention: What do we know now, and when will we know more?

Ian M. Thompson; Joseph Basler; Deborah Hensley; Dendra Von Merveldt; Carol A. Jenkins; Betsy Higgins; Robin Leach; Dean Troyer; Brad Pollock

doi:10.3816/CGC.2003.n.002

Prostate cancer prevention: What do we know now, and when will we know more?

Ian M. Thompson, Joseph Basler, Deborah Hensley, Dendra Von Merveldt, Carol A. Jenkins, Betsy Higgins, Robin Leach, Dean Troyer, Brad Pollock

Research output: Contribution to journal › Review article

8 Scopus citations

Abstract

Prostate cancer prevention is now one of the most aggressively investigated areas of urologic oncology, with > 30,000 men currently participating in clinical trials in the United States alone. The Prostate Cancer Prevention Trial will complete end-of-study prostate biopsies in May 2004, and the Selenium and Vitamin E Cancer Prevention Trial is rapidly reaching its accrual goal 1-2 years ahead of schedule. These 2 studies will give definitive answers regarding 3 of the most important potential preventive interventions: finasteride, vitamin E, and selenium. Many phase II and biomarker-modulation studies are also ongoing, testing a host of other interventions. It is hoped that, within a short period of time, the clinician will be provided with strategies to reduce the risk of the disease.

Original language	English (US)
Pages (from-to)	215-220
Number of pages	6
Journal	Clinical Prostate Cancer
Volume	1
Issue number	4
DOIs	https://doi.org/10.3816/CGC.2003.n.002
State	Published - Mar 2003

Keywords

Biomarker
Early detection
Hormonal agents
Selenium
Vitamin E

ASJC Scopus subject areas

Oncology
Urology

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Thompson, I. M., Basler, J., Hensley, D., Von Merveldt, D., Jenkins, C. A., Higgins, B., Leach, R., Troyer, D., & Pollock, B. (2003). Prostate cancer prevention: What do we know now, and when will we know more? Clinical Prostate Cancer, 1(4), 215-220. https://doi.org/10.3816/CGC.2003.n.002

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abstract = "Prostate cancer prevention is now one of the most aggressively investigated areas of urologic oncology, with > 30,000 men currently participating in clinical trials in the United States alone. The Prostate Cancer Prevention Trial will complete end-of-study prostate biopsies in May 2004, and the Selenium and Vitamin E Cancer Prevention Trial is rapidly reaching its accrual goal 1-2 years ahead of schedule. These 2 studies will give definitive answers regarding 3 of the most important potential preventive interventions: finasteride, vitamin E, and selenium. Many phase II and biomarker-modulation studies are also ongoing, testing a host of other interventions. It is hoped that, within a short period of time, the clinician will be provided with strategies to reduce the risk of the disease.",

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