Prostate cancer detection strategies

Timothy C. Brand, Javier Hernandez, Edith D. Canby-Hagino, Joseph W Basler, Ian M. Thompson

Research output: Contribution to journalArticle

Abstract

Prostate cancer is the most common malignancy in men and, as a result, there has been a nationwide emphasis on screening and detection. With the widespread use of the prostate-specific antigen (PSA), prostate cancer screening effectively detects localized prostate cancer. However, recent reports have identified a significant proportion of prostate cancer in men with low PSA levels. Many of these cancers are higher-grade malignancies. Consequently, PSA may function more effectively as a screening tool when applied over a continuum that is associated with degree of risk, rather than a binary measure. Other markers are currently being investigated. Ideally, a marker will identify the malignancy that is a clinical threat, thereby avoiding intervention for indolent disease. Prevention strategies may be employed for higher-risk patients, and these strategies eventually may be tailored to genetic or other risks.

Original languageEnglish (US)
Pages (from-to)13-17
Number of pages5
JournalCurrent Prostate Reports
Volume5
Issue number1
DOIs
StatePublished - Feb 2007
Externally publishedYes

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Prostatic Neoplasms
Prostate-Specific Antigen
Neoplasms
Early Detection of Cancer

ASJC Scopus subject areas

  • Urology

Cite this

Brand, T. C., Hernandez, J., Canby-Hagino, E. D., Basler, J. W., & Thompson, I. M. (2007). Prostate cancer detection strategies. Current Prostate Reports, 5(1), 13-17. https://doi.org/10.1007/s11918-007-0002-y

Prostate cancer detection strategies. / Brand, Timothy C.; Hernandez, Javier; Canby-Hagino, Edith D.; Basler, Joseph W; Thompson, Ian M.

In: Current Prostate Reports, Vol. 5, No. 1, 02.2007, p. 13-17.

Research output: Contribution to journalArticle

Brand, TC, Hernandez, J, Canby-Hagino, ED, Basler, JW & Thompson, IM 2007, 'Prostate cancer detection strategies', Current Prostate Reports, vol. 5, no. 1, pp. 13-17. https://doi.org/10.1007/s11918-007-0002-y
Brand TC, Hernandez J, Canby-Hagino ED, Basler JW, Thompson IM. Prostate cancer detection strategies. Current Prostate Reports. 2007 Feb;5(1):13-17. https://doi.org/10.1007/s11918-007-0002-y
Brand, Timothy C. ; Hernandez, Javier ; Canby-Hagino, Edith D. ; Basler, Joseph W ; Thompson, Ian M. / Prostate cancer detection strategies. In: Current Prostate Reports. 2007 ; Vol. 5, No. 1. pp. 13-17.
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