Prostaglandins and renal blood flow: In vivo studies

M. D. Lifschitz

Research output: Contribution to journalArticlepeer-review

56 Scopus citations


Data have been reviewed demonstrating that PGE2, PGD2, and PGI2, all of which are produced within the kidney, are direct renal vasodilators when administered to most species. It is possible that one role for these renal vasodilators is to maintain RBF during the stress of acute trauma or surgery. Indeed, prostaglandins may function more as modulators of vasoconstricting actions or mediators of vasodilating actions of other hormones than as direct renal vasodilators themselves.

Original languageEnglish (US)
Pages (from-to)781-785
Number of pages5
JournalKidney international
Issue number6
StatePublished - 1981

ASJC Scopus subject areas

  • Nephrology


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