Propranolol plasma concentrations and plasmapheresis

Robert L. Talbert, Yan Yan Wong, Douglas B. Duncan

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Propranolol plasma concentrations were determined in a patient with hemolytic-uremic syndrome undergoing plasmapheresis before and after the procedure on three occasions. The mean half-life and elimination rate constant during plasmapheresis were estimated to be 25.6 percent of the values obtained without plasmapheresis. These changes suggest that plasmapheresis may influence propranolol disposition.

Original languageEnglish (US)
Pages (from-to)993-996
Number of pages4
JournalAnnals of Pharmacotherapy
Volume15
Issue number12
DOIs
StatePublished - Dec 1981
Externally publishedYes

Keywords

  • hemolytic-uremic syndrome
  • pharmacokinetics
  • plasmapheresis
  • propranolol

ASJC Scopus subject areas

  • Pharmacology (medical)

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