Propoxyphene for Maintenance Treatment of Narcotic Addiction

George E. Woody, Jim Mintz, Forest Tennant, Charles P. O'brien, A. Thomas McLellan, Martin Marcovici

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Two studies compared propoxyphene napsylate (Darvon-N) with methadone hydrochloride as maintenance treatment for narcotic addicts. Most measures indicated that methadone was more effective than propoxyphene as a maintenance drug. Patients receiving propoxyphene reported more withdrawalrelated symptoms early in treatment, tended to drop out sooner than patients receiving methadone, and were more likely to abuse heroin. Nevertheless, follow-up interviews at one and six months after treatment indicated no between-group differences in adjustment.

Original languageEnglish (US)
Pages (from-to)898-900
Number of pages3
JournalArchives of General Psychiatry
Issue number8
StatePublished - Aug 1981
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health


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