Propoxyphene for Maintenance Treatment of Narcotic Addiction

George E. Woody; Jim Mintz; Forest Tennant; Charles P. O'brien; A. Thomas McLellan; Martin Marcovici

doi:10.1001/archpsyc.1981.01780330056005

Propoxyphene for Maintenance Treatment of Narcotic Addiction

George E. Woody, Jim Mintz, Forest Tennant, Charles P. O'brien, A. Thomas McLellan, Martin Marcovici

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Two studies compared propoxyphene napsylate (Darvon-N) with methadone hydrochloride as maintenance treatment for narcotic addicts. Most measures indicated that methadone was more effective than propoxyphene as a maintenance drug. Patients receiving propoxyphene reported more withdrawalrelated symptoms early in treatment, tended to drop out sooner than patients receiving methadone, and were more likely to abuse heroin. Nevertheless, follow-up interviews at one and six months after treatment indicated no between-group differences in adjustment.

Original language	English (US)
Pages (from-to)	898-900
Number of pages	3
Journal	Archives of General Psychiatry
Volume	38
Issue number	8
DOIs	https://doi.org/10.1001/archpsyc.1981.01780330056005
State	Published - Aug 1981
Externally published	Yes

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Psychiatry and Mental health

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10.1001/archpsyc.1981.01780330056005

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author = "Woody, {George E.} and Jim Mintz and Forest Tennant and O'brien, {Charles P.} and McLellan, {A. Thomas} and Martin Marcovici",

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AU - Mintz, Jim

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AU - O'brien, Charles P.

AU - McLellan, A. Thomas

AU - Marcovici, Martin

PY - 1981/8

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AB - Two studies compared propoxyphene napsylate (Darvon-N) with methadone hydrochloride as maintenance treatment for narcotic addicts. Most measures indicated that methadone was more effective than propoxyphene as a maintenance drug. Patients receiving propoxyphene reported more withdrawalrelated symptoms early in treatment, tended to drop out sooner than patients receiving methadone, and were more likely to abuse heroin. Nevertheless, follow-up interviews at one and six months after treatment indicated no between-group differences in adjustment.

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Propoxyphene for Maintenance Treatment of Narcotic Addiction

Abstract

ASJC Scopus subject areas

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