Programmable self-assembly of antibody-oligonucleotide conjugates as small molecule and protein carriers

Amit Gangar, Adrian Fegan, Sidath C. Kumarapperuma, Carston R. Wagner

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Dihydrofolate reductase single-chain variable fragment (scFv) fusion proteins can be used for the targeted cellular delivery of oligonucleotides, conjugated small molecules, and proteins via labeling of oligonucleotides by bis-methotrexate.

Original languageEnglish (US)
Pages (from-to)2895-2897
Number of pages3
JournalJournal of the American Chemical Society
Volume134
Issue number6
DOIs
StatePublished - Feb 15 2012
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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