Program for testing biological interventions to promote healthy aging

Huber R. Warner, Donald Ingram, Richard A. Miller, Nancy L. Nadon, Arlan G. Richardson

Research output: Contribution to journalArticlepeer-review

67 Scopus citations


The National Institute on Aging (NIA) sponsored a workshop on September, 1999 to discuss the feasibility of establishing a program to evaluate potential intervention strategies to decelerate the rate of aging in mammals. The ultimate goal is to identify promising interventions in animals that might lead to clinical trials in humans. The participants discussed various animal models, biological endpoints and possible structure of such a program. The ability to implement such a program will require a decision by NIA staff about whether the anticipated benefits to be derived from identification of effective interventions under well controlled conditions in an animal model, in this case the mouse, would justify the anticipated cost of the testing program. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)199-207
Number of pages9
JournalMechanisms of Ageing and Development
Issue number3
StatePublished - Jun 20 2000


  • Ageing
  • Caloric restriction
  • Human clinical trials

ASJC Scopus subject areas

  • Aging
  • Developmental Biology


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