Prognostic value of exercise-induced ventricular ectopic activity for mortality after acute myocardial infarction

Rodney L. Henry, Gemma T. Kennedy, Michael H. Crawford

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

To evaluate the importance of ventricular ectopic activity on the predischarge treadmill exercise test for predicting mortality in patients after acute myocardial infarction (AMI), 163 patients with uncomplicated AMI were studied using symptom limited low-level treadmill exercise testing and 24-hour ambulatory electrocardiographic monitoring before hospital discharge. All patients were followed for at least 2 years or until recurrent AMI, coronary artery bypass grafting or death. Seventeen patients (10%) died during the follow-up period, 15 patients (9%) had recurrent AMI and 45 patients (28%) underwent bypass surgery. Ventricular ectopic activity was the only single treadmill abnormality that predicted subsequent cardiac death; angina pectoris, electrocardiographic ST-segment depression and a hypotensive blood pressure response did not. The mortality rate in the 20 patients with exercise induced ventricular ectopic activity was 25%, compared with 8% in those without (p < 0.004). Furthermore, in this patient population, exercise-induced ventricular ectopic activity was a much better predictor of cardiac death than that detected by ambulatory monitoring. Thus, ventricular ectopic activity on the predischarge treadmill exercise test is an important risk factor for death after AMI.

Original languageEnglish (US)
Pages (from-to)1251-1255
Number of pages5
JournalThe American journal of cardiology
Volume59
Issue number15
DOIs
StatePublished - Jun 1 1987

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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