Purpose: The development of High Risk Characteristics (HRC, three or more from DRS) has been recognized as a harbinger of Severe Visual Loss (SVL) in patients with Proliferative Diabetic Retinopathy (PDR). This can be reduced by panretinal photocoagulation (PRP) as shown by the DRS. A paucity of data exists prior to vitrectomy (DRVS) and after full scatter treatment, as to the prognostic significance of the persistence of HRC. The purpose of this study is to determine the prognostic significance of the presence of HRC after initial PRP, in terms of severe visual loss (SVL,defined as V.A. of CF or less in two consecutive visits 4 weeks apart) or need for additional PRP or PPV. Methods: We reviewed 220 charts of consecutive patients with PDR and HRC who underwent PRP, 92 charts revealed data that could be analyzed at standardized intervals, and had good photographic documentation. Initial data was analyzed for the risk of development of SVL and the need of additional PRP or PPV, in a two year period. Results: From a total of 19 eyes with persistent HRC 8weeks after initial PRP, 4 eyes (21%) had SVL, 6 eyes (31.58%) needed supplemental photocoagulation and 5 eyes (26.32%) underwent PPV. A total of 12 eyes had no retinopathy risk factors (RRF) or less than HRC 8weeks after initial PRP, none experienced SVL, 4 eyes (33.33%) had additional laser treatment and only 1 eye (8.33%) underwent PPV. Conclusions: Initial data analysis suggests that the presence of HRC, as defined by the DRS, after initial PRP, may be a predictor of severe decrease in V.A. and the need of PPV.
|Original language||English (US)|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Feb 15 1996|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience