Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species

Feng Dong, Youmin Zhong, Bernard Arulanandam, Guangming Zhong

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

We have previously identified a chlamydial protein, chlamydial protease/proteasome-like activity factor (CPAF), for degrading host transcription factors in cells infected with the human chlamydial species Chlamydia trachomaas or Chlamydia pneumoniae. We now report that functional CPAF was also produced during infection with the species Chlamydia muridarum, Chlamydia psittaci, and Chlamydia caviae, which primarily infect nonhuman hosts.

Original languageEnglish (US)
Pages (from-to)1868-1872
Number of pages5
JournalInfection and immunity
Volume73
Issue number3
DOIs
StatePublished - Mar 2005

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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