Prodromal symptoms and signs of bipolar relapse: A report based on prospectively collected data

Emily S. Altman, Margaret M. Rea, Jim Mintz, David J. Miklowitz, Michael J. Goldstein, Sun Hwang

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Prospectively collected data on 19 recently hospitalized patients with bipolar disorder were examined for prodromal changes preceding relapse. The 4-month periods before six manic and six depressive relapses were compared with each other and with a comparable period for seven patients who did not relapse. The Brief Psychiatric Rating Scale was used to assess symptoms. Significant elevations in unusual thought content were found 1 month before manic relapse. Depressive relapsers evidenced higher levels of conceptual disorganization throughout the prerelapse period. Nonrelapsers showed very stable symptom profiles.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalPsychiatry Research
Volume41
Issue number1
DOIs
StatePublished - Jan 1992
Externally publishedYes

Keywords

  • Brief Psychiatric Rating Scale
  • Manic-depression
  • prodrome
  • recurrence

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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