Abstract
Prospectively collected data on 19 recently hospitalized patients with bipolar disorder were examined for prodromal changes preceding relapse. The 4-month periods before six manic and six depressive relapses were compared with each other and with a comparable period for seven patients who did not relapse. The Brief Psychiatric Rating Scale was used to assess symptoms. Significant elevations in unusual thought content were found 1 month before manic relapse. Depressive relapsers evidenced higher levels of conceptual disorganization throughout the prerelapse period. Nonrelapsers showed very stable symptom profiles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Psychiatry Research |
| Volume | 41 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1992 |
| Externally published | Yes |
Keywords
- Brief Psychiatric Rating Scale
- Manic-depression
- prodrome
- recurrence
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
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Altman, E. S., Rea, M. M., Mintz, J., Miklowitz, D. J., Goldstein, M. J., & Hwang, S. (1992). Prodromal symptoms and signs of bipolar relapse: A report based on prospectively collected data. Psychiatry Research, 41(1), 1-8. https://doi.org/10.1016/0165-1781(92)90012-R