Procalcitonin

Philipp Schuetz, Luci K Leykum

Research output: Contribution to journalArticle

Abstract

Procalcitonin (PCT) is the precursor peptide, or prohormone, of the mature hormone calcitonin. Preclinical studies have demonstrated that PCT plays a pathophysiologic role in the development of severe sepsis and sepsis-related mortality, and that the PCT level can be used to help distinguish bacterial and viral infections, at least with respect to respiratory tract infections. PCT also potentially improves risk stratification and decision making with regard to antibiotic therapy in affected patients. This article addresses the use of PCT in the hospital setting regarding the differentiation of respiratory tract infections and guidance for the possible initiation of antibiotic therapy.

Original languageEnglish (US)
JournalHospital Medicine Clinics
Volume1
Issue number3
DOIs
StatePublished - Jul 2012

Fingerprint

Calcitonin
Respiratory Tract Infections
Sepsis
Anti-Bacterial Agents
Virus Diseases
Bacterial Infections
Decision Making
Hormones
Peptides
Mortality
Therapeutics

Keywords

  • Antibiotics
  • Pneumonia
  • Procalcitonin
  • Respiratory infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Procalcitonin. / Schuetz, Philipp; Leykum, Luci K.

In: Hospital Medicine Clinics, Vol. 1, No. 3, 07.2012.

Research output: Contribution to journalArticle

Schuetz, Philipp ; Leykum, Luci K. / Procalcitonin. In: Hospital Medicine Clinics. 2012 ; Vol. 1, No. 3.
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