Primary non-hodgkin lymphoma of the large bowel

Moon June Cho, Chul S. Ha, Pamela K. Allen, Lillian M. Fuller, Fernando Cabanillas, James D. Cox

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

PURPOSE: To characterize the natural history of primary non-Hodgkin lymphoma of the large bowel and identify prognostic factors. MATERIALS AND METHODS: Twenty-three patients with primary non-Hodgkin lymphoma according to strict criteria were identified. Seventeen patients underwent resection, and six patients underwent biopsy. Among 19 patients with intermediate- or high-grade lymphoma, 13 had diffuse large cell lymphoma. Ann Arbor stage was I in 15 cases, II in seven cases, and IV in one case. In 15 patients, the International Prognostic Index was available: 0, eight patients; 1, six patients; and 3, one patient. Postoperatively, six patients received combined chemotherapy and radiation therapy, eight patients received chemotherapy, and six patients received radiation therapy. Overall and relapse-free survival were calculated actuarially, and univariate analysis was performed with regard to stage, treatment, extent of surgery, and the International Prognostic Index. RESULTS: Median follow-up was 144 months. Two patients' disease recurred. Overall and relapse-free survival at 10 years were 61% and 82%, respectively. The International Prognostic Index was the only significant prognostic factor for overall survival (P = .03, log-rank test). CONCLUSION: The prognosis of primary non-Hodgkin lymphoma appears to be as good as that of low- or intermediate-grade lymphoma. The only significant prognostic factor for overall survival is the International Prognostic Index.

Original languageEnglish (US)
Pages (from-to)531-533
Number of pages3
JournalRadiology
Volume205
Issue number2
StatePublished - Dec 1 1997
Externally publishedYes

Keywords

  • Intestinal neoplasms, 75.343
  • Lymphoma, 75.343
  • Lymphoma, therapy, 75.343

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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