Prevalence of smoking and its relationship with carotid atherosclerosis in Alaskan Eskimos of the Norton Sound region: The GOCADAN Study

David J. Kaufman, Mary J. Roman, Richard B. Devereux, Richard R. Fabsitz, Jean W. MacCluer, Bennett Dyke, Sven O.E. Ebbesson, Charlotte R. Wenger, Terry Romanesko, Anthony G. Comuzzie, Barbara V. Howard

    Research output: Contribution to journalArticle

    11 Scopus citations

    Abstract

    Since 2000, the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study has been collecting information on cardiovascular disease (CVD) and its risk factors from 1,214 Alaska Natives of the Norton Sound region, a population with increasing rates of heart disease and stroke. Because smoking was reported in a large proportion of the participants, this analysis was undertaken to evaluate smoking patterns and their relation to other risk factors and to CVD. The relationships among smoking habits and demographic factors, body mass index, plasma fibrinogen, prevalent hypertension, and carotid plaque were evaluated. Eighty percent of participants had smoked 100+ cigarettes in their lifetime. Fifty-seven percent of women and 63% of men (p=.12) were current smokers: one in four smokers had quit. Current smokers (OR=2.1; 95% CI=1.1-3.8) and those who had quit <5 years ago (OR=1.6; 95% CI=1.1-2.2) were more likely than non-smokers to have carotid plaque. Pack-years smoked also were correlated with carotid plaque. The high prevalence of smoking and low rates of cessation in this population demonstrate an urgent need for smoking prevention and cessation programs among Alaskan Eskimos of the Norton Sound region and other Alaska Native groups.

    Original languageEnglish (US)
    Pages (from-to)483-491
    Number of pages9
    JournalNicotine and Tobacco Research
    Volume10
    Issue number3
    DOIs
    StatePublished - Mar 1 2008

    ASJC Scopus subject areas

    • Public Health, Environmental and Occupational Health

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    Kaufman, D. J., Roman, M. J., Devereux, R. B., Fabsitz, R. R., MacCluer, J. W., Dyke, B., Ebbesson, S. O. E., Wenger, C. R., Romanesko, T., Comuzzie, A. G., & Howard, B. V. (2008). Prevalence of smoking and its relationship with carotid atherosclerosis in Alaskan Eskimos of the Norton Sound region: The GOCADAN Study. Nicotine and Tobacco Research, 10(3), 483-491. https://doi.org/10.1080/14622200801901955