Prevalence of serum antibodies against lymphocytic choriomeningitis virus in selected populations from two U.S. cities

Charles B. Stephensen, Sharon R. Blount, Robert E. Lanford, Kathryn V. Holmes, Richard J. Montali, Michael E. Fleenor, Joseph F.E. Shaw

    Research output: Contribution to journalArticle

    41 Scopus citations

    Abstract

    An ELISA was developed for measuring serum antibodies against the arenavirus lymphocytic choriomeningitis virus (LCMV) and a closely related isolate termed callitrichid hepatitis virus (CHV). The ELISA was used to test sera from healthy adults and from hepatitis patients. In Birmingham, Alabama, the seropositivity rate for healthy black women was 5.1% (7/138), and the rate for patients with all types of hepatitis or cirrhosis was 4.3% (2/46). In San Antonio, Texas, the seropositivity rate among a clinical series of patients with non‐A, non‐B hepatitis was 0 (0/20), and the rate among persons rejected from blood donation because of high serum alanine aminotransferase levels was 2.4% (2/82). These results indicate that infection with LCMV or CHV is common in Birmingham but that infection is not associated with hepatitis. © 1992 Wiley‐Liss, Inc.

    Original languageEnglish (US)
    Pages (from-to)27-31
    Number of pages5
    JournalJournal of Medical Virology
    Volume38
    Issue number1
    DOIs
    StatePublished - Sep 1992

    Keywords

    • arenavirus
    • callitrichid
    • hepatitis

    ASJC Scopus subject areas

    • Virology
    • Infectious Diseases

    Fingerprint Dive into the research topics of 'Prevalence of serum antibodies against lymphocytic choriomeningitis virus in selected populations from two U.S. cities'. Together they form a unique fingerprint.

  • Cite this

    Stephensen, C. B., Blount, S. R., Lanford, R. E., Holmes, K. V., Montali, R. J., Fleenor, M. E., & Shaw, J. F. E. (1992). Prevalence of serum antibodies against lymphocytic choriomeningitis virus in selected populations from two U.S. cities. Journal of Medical Virology, 38(1), 27-31. https://doi.org/10.1002/jmv.1890380107