Prevalence of group B streptococcus colonization in subsequent pregnancies of group B streptococcus-colonized versus noncolonized women

Sarah M. Page-Ramsey, Sara K. Johnstone, David Kim, Patrick S. Ramsey

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Objective To determine whether group B Streptococcus (GBS)-colonized pregnant women have an increased prevalence of GBS colonization in subsequent pregnancies. Study Design This retrospective cohort study compared the prevalence of GBS colonization in initial and subsequent pregnancies of 158 women with two or more deliveries at a Midwest institution since the initiation of universal screening for GBS. Results The GBS colonization rate in index pregnancies was 20%. Colonization rate in subsequent pregnancies for initially GBS-colonized women was 42% compared with 19% for women who were not colonized with GBS in the index pregnancy (p = 0.009). The relative risk for GBS-colonized women to be GBS-colonized in subsequent pregnancies was 2.2 (confidence interval = 1.3 to 3.8). Conclusion Previous GBS colonization is a risk factor for GBS colonization in subsequent pregnancies. Consideration of intrapartum chemoprophylaxis in women with a history of GBS colonization, assuming current colonization status is unknown, warrants further investigation.

Original languageEnglish (US)
Pages (from-to)383-388
Number of pages6
JournalAmerican Journal of Perinatology
Volume30
Issue number5
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

Keywords

  • GBS
  • group B Streptococcus
  • pregnancy
  • Streptococcus agalactiae

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Prevalence of group B streptococcus colonization in subsequent pregnancies of group B streptococcus-colonized versus noncolonized women'. Together they form a unique fingerprint.

  • Cite this