Prescribed and Measured Dose Differences for an AP-PA TBI Protocol with Compensation Filter and Ergonomic Patient Support

Francisco Mesa Linares, Nikos Papanikolaou, Carlos Esquivel, Tony Y. Eng, Clifton D. Fuller, Modesto Sosa

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Introduction A treatment scheme is presented for clinical applications of total body radiation using 6 MV photons. Methods The two-field technique, anteroposterior (AP) and posteroanterior (PA), was applied. In vivo dose verification with TLD-100 dosimeters was developed during the first treatment sessions. Dosimetry was performed in several anatomical regions such as head, shoulder, thorax, abdomen, hip, thigh, knee, and ankle in 13 patients as preconditioning for bone marrow transplantation. A prescribed dose of 100 cGy was considered at the level of the patient's coronal plane. Values with least differences between measured and prescribed dose were obtained for the shoulder. Results Standard deviation percentages of 0.3% and 2.6% were recorded between these doses for AP and PA, respectively. There were larger differences for other contours. In general, a measured dose less than the prescribed dose was observed in all the contours. Conclusion Differences between prescribed and measured doses showed in this study can contribute to a required understanding about the accurate doses in AP-PA total body irradiation (TBI) treatments.

Original languageEnglish (US)
Pages (from-to)301-306
Number of pages6
JournalJournal of Medical Imaging and Radiation Sciences
Volume48
Issue number3
DOIs
StatePublished - Sep 2017

Keywords

  • AP-PA
  • bone marrow
  • dose calculation
  • radiotherapy
  • total body irradiation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Prescribed and Measured Dose Differences for an AP-PA TBI Protocol with Compensation Filter and Ergonomic Patient Support'. Together they form a unique fingerprint.

Cite this