Preliminary results of temporary placement of retrievable expandable metallic stents during preoperative neoadjuvant chemoradiotherapy in patients with resectable esophageal cancer

Jung Hoon Park, Ho Young Song, Ji Hoon Shin, Jin Hyoung Kim, Yong Hee Kim, Sung Bae Kim, Jong Hoon Kim

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Purpose To evaluate the clinical efficacy of temporary placement of a retrievable expandable metallic stent (REMS) during preoperative neoadjuvant chemoradiotherapy (CRT) in patients with resectable esophageal cancer. Materials and Methods REMSs were placed in 25 patients who underwent preoperative neoadjuvant CRT for resectable esophageal cancer. Stent removal was scheduled between 4 and 6 weeks after starting neoadjuvant CRT. Clinical effectiveness was assessed using the following variables: technical and clinical success, dysphagia score before and after stent placement and removal, and complications and their management. Results REMS placement was technically successful in all patients, with 24 of 25 patients (96%) showing symptomatic improvement. Stents were removed electively 32 days (range, 27-42 d) after starting neoadjuvant CRT (n = 20; 80%) or after stent migration and exit through the anus with no evidence of symptom recurrence (n = 5; 20%). The dysphagia score (before stent, 3.1 ± 0.5) improved by 3 days after stent placement (1.3 ± 0.4; P <.001) and was maintained up to 1 month after stent removal (1.2 ± 0.7; P <.001). The median survival was 18.6 months. Conclusions In patients with resectable esophageal cancer, temporary placement of a REMS during preoperative neoadjuvant CRT showed clinical efficacy in the bridge to surgery. Stent removal between 4 and 6 weeks after starting neoadjuvant CRT seems to be a feasible time frame with symptom improvement.

Original languageEnglish (US)
Pages (from-to)883-888
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume26
Issue number6
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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