PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS

S. Cats, S. Perdue, P. I. Terasaki, M. R. Mickey

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Glomerulonephritis patients transplanted with cadaver kidneys had a significantly higher one-year graft survival when immunosuppressed with cyclosporin rather than standard therapy (80% versus 59%, p<10-5). For nephrosclerosis patients the corresponding rates were 70% and 59% (p>0·05); and in those with antecedent diabetes mellitus, polycystic kidney, and pyelonephritis the differences were negligible. In glomerulonephritis patients, but not in the other groups, cyclosporin was additive to the effect of transfusions and of HLA-A, B and HLA-Dr matching.

Original languageEnglish (US)
Pages (from-to)490-491
Number of pages2
JournalThe Lancet
Volume325
Issue number8427
DOIs
StatePublished - Mar 2 1985
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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