PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS

S. Cats; S. Perdue; P. I. Terasaki; M. R. Mickey

doi:10.1016/S0140-6736(85)92090-2

PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS

S. Cats, S. Perdue, P. I. Terasaki, M. R. Mickey

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Glomerulonephritis patients transplanted with cadaver kidneys had a significantly higher one-year graft survival when immunosuppressed with cyclosporin rather than standard therapy (80% versus 59%, p<10^-5). For nephrosclerosis patients the corresponding rates were 70% and 59% (p>0·05); and in those with antecedent diabetes mellitus, polycystic kidney, and pyelonephritis the differences were negligible. In glomerulonephritis patients, but not in the other groups, cyclosporin was additive to the effect of transfusions and of HLA-A, B and HLA-Dr matching.

Original language	English (US)
Pages (from-to)	490-491
Number of pages	2
Journal	The Lancet
Volume	325
Issue number	8427
DOIs	https://doi.org/10.1016/S0140-6736(85)92090-2
State	Published - Mar 2 1985
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/S0140-6736(85)92090-2

Cite this

@article{ad1b95ea15f546df9301a74024ad634a,

title = "PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS",

abstract = "Glomerulonephritis patients transplanted with cadaver kidneys had a significantly higher one-year graft survival when immunosuppressed with cyclosporin rather than standard therapy (80% versus 59%, p<10-5). For nephrosclerosis patients the corresponding rates were 70% and 59% (p>0·05); and in those with antecedent diabetes mellitus, polycystic kidney, and pyelonephritis the differences were negligible. In glomerulonephritis patients, but not in the other groups, cyclosporin was additive to the effect of transfusions and of HLA-A, B and HLA-Dr matching.",

author = "S. Cats and S. Perdue and Terasaki, {P. I.} and Mickey, {M. R.}",

year = "1985",

month = mar,

day = "2",

doi = "10.1016/S0140-6736(85)92090-2",

language = "English (US)",

volume = "325",

pages = "490--491",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

number = "8427",

}

TY - JOUR

T1 - PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS

AU - Cats, S.

AU - Perdue, S.

AU - Terasaki, P. I.

AU - Mickey, M. R.

PY - 1985/3/2

Y1 - 1985/3/2

N2 - Glomerulonephritis patients transplanted with cadaver kidneys had a significantly higher one-year graft survival when immunosuppressed with cyclosporin rather than standard therapy (80% versus 59%, p<10-5). For nephrosclerosis patients the corresponding rates were 70% and 59% (p>0·05); and in those with antecedent diabetes mellitus, polycystic kidney, and pyelonephritis the differences were negligible. In glomerulonephritis patients, but not in the other groups, cyclosporin was additive to the effect of transfusions and of HLA-A, B and HLA-Dr matching.

AB - Glomerulonephritis patients transplanted with cadaver kidneys had a significantly higher one-year graft survival when immunosuppressed with cyclosporin rather than standard therapy (80% versus 59%, p<10-5). For nephrosclerosis patients the corresponding rates were 70% and 59% (p>0·05); and in those with antecedent diabetes mellitus, polycystic kidney, and pyelonephritis the differences were negligible. In glomerulonephritis patients, but not in the other groups, cyclosporin was additive to the effect of transfusions and of HLA-A, B and HLA-Dr matching.

UR - http://www.scopus.com/inward/record.url?scp=0021985040&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021985040&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(85)92090-2

DO - 10.1016/S0140-6736(85)92090-2

M3 - Article

C2 - 2857855

AN - SCOPUS:0021985040

VL - 325

SP - 490

EP - 491

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 8427

ER -

PREFERENTIAL EFFECTIVENESS OF CYCLOSPORIN IN PATIENTS RECEIVING KIDNEY TRANSPLANTS AFTER GLOMERULONEPHRITIS

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this