Predictors of the rate of renal function decline in non-insulin-dependent diabetes mellitus

Rodolfo Garza, Rolando Medina, Srabashi Basu, Jacqueline A. Pugh

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

A multivariate analysis of 263 Mexican-American, African-American, and Non-Hispanic white non-insulin-dependent diabetes mellitus patients with end-stage renal disease revealed that in subjects following a linear course of decline of renal function, Mexican-American ethnicity (p = 0.0503) and female sex (p = 0.0036) hasten the rate of decline of renal function, while age (p = 0.0004), hypertension duration (p = 0.0058), and diabetes duration (p = 0.0587) slow the rate of decline of renal function. Blood pressure and glycemic control do not predict the rate of decline. These data suggest that ethnicity and sex-related factors may be as important as blood pressure and glycemic control during the course of non-insulin-dependent diabetic nephropathy.

Original languageEnglish (US)
Pages (from-to)59-67
Number of pages9
JournalAmerican journal of nephrology
Volume17
Issue number1
DOIs
StatePublished - 1997

Keywords

  • Chronic
  • Decline
  • Diabetes mellitus
  • Kidney failure
  • Progression
  • Renal disease
  • Renal function

ASJC Scopus subject areas

  • Nephrology

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