TY - JOUR
T1 - Predictors of outcomes in the treatment of urge urinary incontinence in women
AU - Richter, Holly E.
AU - Burgio, Kathryn L.
AU - Chai, Toby C.
AU - Kraus, Stephen R.
AU - Xu, Yan
AU - Nyberg, Lee
AU - Brubaker, Linda
PY - 2009
Y1 - 2009
N2 - Introduction and hypothesis: Women with urge predominant urinary incontinence received active intervention (drug therapy alone or combined with behavioral therapy) for 10 weeks, then stopped all therapy and were followed for 6 months more. In this planned secondary analysis, we aimed to identify predictors of therapeutic success at 10 weeks (≥70% reduction in incontinence) and of ability to discontinue treatment and sustain improvements 6 months later. Methods: Using data from 307 women, we performed logistic regression to identify predictors for outcomes described above. Results: After controlling for group, only younger age was associated with short-term success (OR 0.8, 95% CI 0.66, 0.96). At 6 months, controlling for group and short-term outcome, only greater anterior vaginal wall prolapse was associated with successful discontinuation (POP-Q point Aa; OR 1.33, 95% CI 1.03, 1.7). Conclusion: These findings are not of sufficient strength to justify withholding conservative therapies but might be used to promote realistic expectations when counseling patients.
AB - Introduction and hypothesis: Women with urge predominant urinary incontinence received active intervention (drug therapy alone or combined with behavioral therapy) for 10 weeks, then stopped all therapy and were followed for 6 months more. In this planned secondary analysis, we aimed to identify predictors of therapeutic success at 10 weeks (≥70% reduction in incontinence) and of ability to discontinue treatment and sustain improvements 6 months later. Methods: Using data from 307 women, we performed logistic regression to identify predictors for outcomes described above. Results: After controlling for group, only younger age was associated with short-term success (OR 0.8, 95% CI 0.66, 0.96). At 6 months, controlling for group and short-term outcome, only greater anterior vaginal wall prolapse was associated with successful discontinuation (POP-Q point Aa; OR 1.33, 95% CI 1.03, 1.7). Conclusion: These findings are not of sufficient strength to justify withholding conservative therapies but might be used to promote realistic expectations when counseling patients.
KW - Predictors of outcome
KW - Randomized trial
KW - Urge urinary incontinence
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U2 - 10.1007/s00192-009-0805-1
DO - 10.1007/s00192-009-0805-1
M3 - Article
C2 - 19183825
AN - SCOPUS:63749098726
VL - 20
SP - 489
EP - 497
JO - International Urogynecology Journal and Pelvic Floor Dysfunction
JF - International Urogynecology Journal and Pelvic Floor Dysfunction
SN - 0937-3462
IS - 5
ER -