TY - JOUR
T1 - Prebiotic Intake in Older Adults
T2 - Effects on Brain Function and Behavior
AU - Serra, Monica C.
AU - Nocera, Joe R.
AU - Kelleher, Jessica L.
AU - Addison, Odessa
N1 - Publisher Copyright:
© 2019, This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Purpose of Review: This literature review summarizes the evidence for and against the impact of prebiotics on brain function and behavior in older adults. Recent Findings: Current evidence generally supports the intake of prebiotics to increase beneficial gut bacteria concentrations. These bacteria appear to impact endocrine, immunologic, and neuronal communication along the gut-brain axis to alter brain function and behavior. Summary: Preliminary evidence in human studies consistently support prebiotics doses of ~ 5–10 g/d as safe to improve brain function (i.e., learning and working memory) and behavior (i.e., anxiety and mood). However, these studies are mainly of short duration (4–12 weeks) and limited to healthy, young, and middle-aged adults. More research is needed to identify a safe and effective dose, duration, and delivery method, particularly among diseased, older adults.
AB - Purpose of Review: This literature review summarizes the evidence for and against the impact of prebiotics on brain function and behavior in older adults. Recent Findings: Current evidence generally supports the intake of prebiotics to increase beneficial gut bacteria concentrations. These bacteria appear to impact endocrine, immunologic, and neuronal communication along the gut-brain axis to alter brain function and behavior. Summary: Preliminary evidence in human studies consistently support prebiotics doses of ~ 5–10 g/d as safe to improve brain function (i.e., learning and working memory) and behavior (i.e., anxiety and mood). However, these studies are mainly of short duration (4–12 weeks) and limited to healthy, young, and middle-aged adults. More research is needed to identify a safe and effective dose, duration, and delivery method, particularly among diseased, older adults.
KW - Aging
KW - Brain health
KW - Cognitive function
KW - Prebiotics
KW - Supplementation
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U2 - 10.1007/s13668-019-0265-2
DO - 10.1007/s13668-019-0265-2
M3 - Review article
C2 - 30888666
AN - SCOPUS:85065455207
SN - 2161-3311
VL - 8
SP - 66
EP - 73
JO - Current Nutrition Reports
JF - Current Nutrition Reports
IS - 2
ER -