Prazosin for military combat-related PTSD nightmares: A critical review

Brian W. Writer, Eric G. Meyer, Jason E. Schillerstrom

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Military combat is a common trauma experience associated with posttraumatic stress disorder (PTSD). Trauma-related nightmares are a hallmark symptom of PTSD. They can be resistant to label-pharmacological PTSD treatment, and they are associated with a variety of adverse health outcomes. The purpose of this article is to review and evaluate prazosin therapy for combat-related PTSD nightmares. Consistent with available literature for all-causes PTSD nightmares, prazosin is an effective off-label option for combat-related PTSD nightmares. Future trials may further instruct use in specific combat-exposure profiles.

Original languageEnglish (US)
Pages (from-to)24-33
Number of pages10
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume26
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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