Potassium channelopathies of epilepsy

Robert Brenner, Karen S. Wilcox

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The potassium channel family represents a large group with diverse functional roles. Not surprisingly, the list of potassium channelopathies contributing to human epilepsy has greatly expanded. The focus of this chapter will be the causative role in epilepsy of mutations in potassium channels and associated regulatory proteins. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at).

Original languageEnglish (US)
Number of pages1
JournalEpilepsia
Volume51
Issue numberSUPPL. 5
DOIs
StatePublished - Dec 1 2010

Keywords

  • A-type current
  • Benign familial neonatal convulsions
  • Calcium-gated channel
  • Gene mutations
  • Inward rectifier
  • Regulatory protein
  • Seizures
  • Voltage-gated channel

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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