Postmenopausal hypertension: Insights from rat models

Licy L. Yanes, Lourdes A. Fortepiani, Julio C. Sartori-Valinotti, Radu Iliescu, Jane F. Reckelhoff

Research output: Contribution to journalReview article

Abstract

The increase in blood pressure following menopause sets women up for increased risk of negative cardiovascular outcomes. The increase in blood pressure occurs 5-10 years following cessation of menses which suggests that mechanisms other than loss of female sex hormones may play roles in mediating the hypertension. Recent studies using rat models of aging have began to shed light on some of possible mechanisms responsible for postmenopausal hypertension. This review outlines the most recent studies and addresses questions remaining to be addressed.

Original languageEnglish (US)
Pages (from-to)177-181
Number of pages5
JournalCurrent Hypertension Reviews
Volume3
Issue number3
DOIs
StatePublished - Aug 1 2007
Externally publishedYes

Keywords

  • Dahl salt sensitive rats
  • Endothelin
  • Metabolic syndrome
  • Oxidative stress
  • Renin-angiotensin
  • Spontaneously hypertensive rats
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Internal Medicine

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  • Cite this

    Yanes, L. L., Fortepiani, L. A., Sartori-Valinotti, J. C., Iliescu, R., & Reckelhoff, J. F. (2007). Postmenopausal hypertension: Insights from rat models. Current Hypertension Reviews, 3(3), 177-181. https://doi.org/10.2174/157340207781386756