TY - JOUR
T1 - Posterior segment manifestations of Takayasu arteritis
T2 - A narrative review
AU - Sharma, Unnati
AU - Rishi, Ekta
AU - Rishi, Pukhraj
AU - Gupta, Vishali
AU - Raman, Rajiv
N1 - Publisher Copyright:
© 2024 Copyright:
PY - 2024/5
Y1 - 2024/5
N2 - Ocular symptoms can be the presenting manifestation of Takayasu arteritis (TA) or could be indicative of disease reactivation. A review of published literature related to posterior segment manifestations of TA by using the keywords 'Takayasu arteritis,' 'ophthalmic manifestations,' 'retina,' 'retinopathy,' 'ocular,' 'optic nerve,' and 'optic neuropathy' was performed. In total, 62 case reports and 12 case series were included. The majority of the articles were from Asia (n = 47, 64%). Females outnumbered males in the ratio of 7:1. The mean age of patients was 33 years (range: 8-78 years, SD: 13.5 years). In 58% (n = 41 out of 71) cases, ocular symptoms were the presenting manifestation of the underlying disease. Hypotensive retinopathy was found in 70% of eyes, and hypertensive retinopathy was found in 27%. The mean presenting visual acuity (VA) was +1.03 logMAR (range: -0.12 to 3, SD: 1.07), and at the final follow-up was +1.02 logMAR (range: -0.12 to 3, SD 1.17). VA improved in 34% (n = 29/86), remained stable in 45% (39/86), and worsened in 21% (18/86). The mean follow-up was 9 months (range: 0.5-204, SD: 16 months).
AB - Ocular symptoms can be the presenting manifestation of Takayasu arteritis (TA) or could be indicative of disease reactivation. A review of published literature related to posterior segment manifestations of TA by using the keywords 'Takayasu arteritis,' 'ophthalmic manifestations,' 'retina,' 'retinopathy,' 'ocular,' 'optic nerve,' and 'optic neuropathy' was performed. In total, 62 case reports and 12 case series were included. The majority of the articles were from Asia (n = 47, 64%). Females outnumbered males in the ratio of 7:1. The mean age of patients was 33 years (range: 8-78 years, SD: 13.5 years). In 58% (n = 41 out of 71) cases, ocular symptoms were the presenting manifestation of the underlying disease. Hypotensive retinopathy was found in 70% of eyes, and hypertensive retinopathy was found in 27%. The mean presenting visual acuity (VA) was +1.03 logMAR (range: -0.12 to 3, SD: 1.07), and at the final follow-up was +1.02 logMAR (range: -0.12 to 3, SD 1.17). VA improved in 34% (n = 29/86), remained stable in 45% (39/86), and worsened in 21% (18/86). The mean follow-up was 9 months (range: 0.5-204, SD: 16 months).
KW - Ischemic retinopathy
KW - Takayasu arteritis
KW - Takayasu retinopathy
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U2 - 10.4103/IJO.IJO_1346_23
DO - 10.4103/IJO.IJO_1346_23
M3 - Review article
C2 - 38648432
AN - SCOPUS:85190974013
SN - 0301-4738
VL - 72
SP - 637
EP - 647
JO - Indian Journal of Ophthalmology
JF - Indian Journal of Ophthalmology
IS - 5
ER -