Posterior segment manifestations of Takayasu arteritis: A narrative review

Unnati Sharma, Ekta Rishi, Pukhraj Rishi, Vishali Gupta, Rajiv Raman

Research output: Contribution to journalReview articlepeer-review

Abstract

Ocular symptoms can be the presenting manifestation of Takayasu arteritis (TA) or could be indicative of disease reactivation. A review of published literature related to posterior segment manifestations of TA by using the keywords 'Takayasu arteritis,' 'ophthalmic manifestations,' 'retina,' 'retinopathy,' 'ocular,' 'optic nerve,' and 'optic neuropathy' was performed. In total, 62 case reports and 12 case series were included. The majority of the articles were from Asia (n = 47, 64%). Females outnumbered males in the ratio of 7:1. The mean age of patients was 33 years (range: 8-78 years, SD: 13.5 years). In 58% (n = 41 out of 71) cases, ocular symptoms were the presenting manifestation of the underlying disease. Hypotensive retinopathy was found in 70% of eyes, and hypertensive retinopathy was found in 27%. The mean presenting visual acuity (VA) was +1.03 logMAR (range: -0.12 to 3, SD: 1.07), and at the final follow-up was +1.02 logMAR (range: -0.12 to 3, SD 1.17). VA improved in 34% (n = 29/86), remained stable in 45% (39/86), and worsened in 21% (18/86). The mean follow-up was 9 months (range: 0.5-204, SD: 16 months).

Original languageEnglish (US)
Pages (from-to)637-647
Number of pages11
JournalIndian Journal of Ophthalmology
Volume72
Issue number5
DOIs
StatePublished - May 2024

Keywords

  • Ischemic retinopathy
  • Takayasu arteritis
  • Takayasu retinopathy

ASJC Scopus subject areas

  • Ophthalmology

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