Posterior cortical atrophy with right lower egocentric quadrantic neglect and lower vertical allocentric neglect

Usama Tariq, Alicia Parker, Leila Saadatpour, Leilani Doty, Kenneth M. Heilman

Research output: Contribution to journalArticlepeer-review

Abstract

Background/Objectives: Whereas rare cases of hemispatial visual neglect have been reported in patients with a neurodegenerative disease, quadrantic visuospatial neglect has not been described.We report a patient with probable posterior cortical atrophy who demonstrated lower right-sided quadrantic visuospatial neglect, together with allocentric vertical neglect. Methods/Results: A 68-year-old man initially noted deficits in reading and writing. Subsequently, he developed other cognitive deficits.On vertical line bisections, he deviated upward, and on horizontal line bisections, he deviated to the left. These deviations together suggest that this man's neglect might be most severe in his right (head/body-centered) lower (below eye level) visual space. When attempting to perform vertical line bisections in all four egocentric quadrants, his upward deviations were largest in the right lower quadrant. On a cancelation test, he revealed bilateral lower (ventral) allocentric neglect but not egocentric neglect. This patient's magnetic resonance imaging revealed cortical atrophy, most prominent in the left parietal lobe. Discussion: Previous research in stroke patients has demonstrated that the parietal lobes are important in mediating attention to contralateral and inferior visual space. The presence of left parietal atrophy may have induced this right lower (ventral) egocentric inattention as well as bilateral ventral allocentric inattention. Although to our knowledge there have been no prior reports of a patient with right lower quadrantic and lower vertical allocentric visuospatial neglect, patients are rarely tested for these forms of neglect, and this patient illustrates the importance of evaluating patients for these and other forms of neglect.

Original languageEnglish (US)
Pages (from-to)448-457
Number of pages10
JournalArchives of Clinical Neuropsychology
Volume35
Issue number4
DOIs
StatePublished - 2021

Keywords

  • Alzheimer's disease
  • Neurodegenerative disease
  • Posterior cortical atrophy
  • Quadrantic neglect
  • Spatial inattention

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Psychiatry and Mental health

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