Post-thrombotic syndrome is uncommon in childhood cancer survivors

Janna M. Journeycake, Debra Eshelman, George R. Buchanan

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Deep vein thrombosis occurs in up to 50% of children with tunneled central venous catheters (CVCs). CVC-related deep vein thrombosis involving the upper extremity is usually asymptomatic but can result in post-thrombotic syndrome (swelling, pain, skin changes, and functional impairment). In a cohort of childhood cancer survivors evaluated clinically a mean of 7.5 ± 2.8 years after completion of therapy who previously had CVCs in place for a median 15.5 months, none of 50 patients (95% CI ∇ 0% to 6%) had these features diagnostic of post-thrombotic syndrome. Five patients had arm circumference 3% to 5% greater ipsilateral to the prior CVC.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalJournal of Pediatrics
Issue number2
StatePublished - Feb 2006
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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