Portable oral cancer detection using miniature confocal imaging probe with large field of view

Youmin Wang; Milan Raj; H. Stan McGuff; Ting Shen; Xiaojing Zhang

doi:10.1109/TRANSDUCERS.2011.5969765

Portable oral cancer detection using miniature confocal imaging probe with large field of view

Youmin Wang, Milan Raj, H. Stan McGuff, Ting Shen, Xiaojing Zhang

Pathology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

We demonstrate MEMS micromirror enabled hand-held confocal imaging probe for portable oral cancer detection, where large field of view (FOV) is achieved through the lissajous scanning operation of the MEMS mirror. The imaging speed up to 2 frames per second was demonstrated with the improved Labview and Java based data acquisition and control programs. We also examined the axial resolution (3.4 um) and large FOV (1mm × 1mm) through mosaic imaging using the handheld imaging probe. Multiple clinical samples, including neoplastic lesion tissues of giant cell fibroma, epithelial ossifying fibroma, the fibroma inside the paraffin box and ex-vivo gross tissue, were scanned using the compact imaging modalities. The quality of the images acquired is comparable to those from commercial microscopes.

Original language	English (US)
Title of host publication	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages	1821-1824
Number of pages	4
DOIs	https://doi.org/10.1109/TRANSDUCERS.2011.5969765
State	Published - Sep 1 2011
Event	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China Duration: Jun 5 2011 → Jun 9 2011

Publication series

Name	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Other

Other	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/Territory	China
City	Beijing
Period	6/5/11 → 6/9/11

Keywords

Confocal endoscopy
Micro-electromechanical system (MEMS)
Micromirror
oral cancer

ASJC Scopus subject areas

Hardware and Architecture
Electrical and Electronic Engineering

Access to Document

10.1109/TRANSDUCERS.2011.5969765

Cite this

Wang, Y., Raj, M., McGuff, H. S., Shen, T., & Zhang, X. (2011). Portable oral cancer detection using miniature confocal imaging probe with large field of view. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 (pp. 1821-1824). [5969765] (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). https://doi.org/10.1109/TRANSDUCERS.2011.5969765

Portable oral cancer detection using miniature confocal imaging probe with large field of view. / Wang, Youmin; Raj, Milan; McGuff, H. Stan; Shen, Ting; Zhang, Xiaojing.

2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 1821-1824 5969765 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Wang, Y, Raj, M, McGuff, HS, Shen, T & Zhang, X 2011, Portable oral cancer detection using miniature confocal imaging probe with large field of view. in 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11., 5969765, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, pp. 1821-1824, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, Beijing, China, 6/5/11. https://doi.org/10.1109/TRANSDUCERS.2011.5969765

Wang Y, Raj M, McGuff HS, Shen T, Zhang X. Portable oral cancer detection using miniature confocal imaging probe with large field of view. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 1821-1824. 5969765. (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). https://doi.org/10.1109/TRANSDUCERS.2011.5969765

Wang, Youmin ; Raj, Milan ; McGuff, H. Stan ; Shen, Ting ; Zhang, Xiaojing. / Portable oral cancer detection using miniature confocal imaging probe with large field of view. 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. pp. 1821-1824 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11).

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abstract = "We demonstrate MEMS micromirror enabled hand-held confocal imaging probe for portable oral cancer detection, where large field of view (FOV) is achieved through the lissajous scanning operation of the MEMS mirror. The imaging speed up to 2 frames per second was demonstrated with the improved Labview and Java based data acquisition and control programs. We also examined the axial resolution (3.4 um) and large FOV (1mm × 1mm) through mosaic imaging using the handheld imaging probe. Multiple clinical samples, including neoplastic lesion tissues of giant cell fibroma, epithelial ossifying fibroma, the fibroma inside the paraffin box and ex-vivo gross tissue, were scanned using the compact imaging modalities. The quality of the images acquired is comparable to those from commercial microscopes.",

keywords = "Confocal endoscopy, Micro-electromechanical system (MEMS), Micromirror, oral cancer",

author = "Youmin Wang and Milan Raj and McGuff, {H. Stan} and Ting Shen and Xiaojing Zhang",

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N2 - We demonstrate MEMS micromirror enabled hand-held confocal imaging probe for portable oral cancer detection, where large field of view (FOV) is achieved through the lissajous scanning operation of the MEMS mirror. The imaging speed up to 2 frames per second was demonstrated with the improved Labview and Java based data acquisition and control programs. We also examined the axial resolution (3.4 um) and large FOV (1mm × 1mm) through mosaic imaging using the handheld imaging probe. Multiple clinical samples, including neoplastic lesion tissues of giant cell fibroma, epithelial ossifying fibroma, the fibroma inside the paraffin box and ex-vivo gross tissue, were scanned using the compact imaging modalities. The quality of the images acquired is comparable to those from commercial microscopes.

AB - We demonstrate MEMS micromirror enabled hand-held confocal imaging probe for portable oral cancer detection, where large field of view (FOV) is achieved through the lissajous scanning operation of the MEMS mirror. The imaging speed up to 2 frames per second was demonstrated with the improved Labview and Java based data acquisition and control programs. We also examined the axial resolution (3.4 um) and large FOV (1mm × 1mm) through mosaic imaging using the handheld imaging probe. Multiple clinical samples, including neoplastic lesion tissues of giant cell fibroma, epithelial ossifying fibroma, the fibroma inside the paraffin box and ex-vivo gross tissue, were scanned using the compact imaging modalities. The quality of the images acquired is comparable to those from commercial microscopes.

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Portable oral cancer detection using miniature confocal imaging probe with large field of view

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