Pneumococci: Immunology of the innate host response

Gavin K. Paterson; Carlos J. Orihuela

doi:10.1111/j.1440-1843.2010.01814.x

Pneumococci: Immunology of the innate host response

Gavin K. Paterson, Carlos J. Orihuela

Microbiology, Immunology & Molecular Genetics

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

Original language	English (US)
Pages (from-to)	1057-1063
Number of pages	7
Journal	Respirology
Volume	15
Issue number	7
DOIs	https://doi.org/10.1111/j.1440-1843.2010.01814.x
State	Published - Oct 2010

Keywords

Streptococcus pneumoniae
Toll-like receptor
infectious disease
innate immunity
pattern recognition receptor

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1111/j.1440-1843.2010.01814.x

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