Pneumococci: Immunology of the innate host response

Gavin K. Paterson, Carlos J. Orihuela

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

Original languageEnglish (US)
Pages (from-to)1057-1063
Number of pages7
JournalRespirology
Volume15
Issue number7
DOIs
StatePublished - Oct 2010

Keywords

  • Streptococcus pneumoniae
  • Toll-like receptor
  • infectious disease
  • innate immunity
  • pattern recognition receptor

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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