Pneumococci: Immunology of the innate host response

Gavin K. Paterson; Carlos J. Orihuela

doi:10.1111/j.1440-1843.2010.01814.x

Pneumococci: Immunology of the innate host response

Gavin K. Paterson, Carlos J. Orihuela

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

Original language	English (US)
Pages (from-to)	1057-1063
Number of pages	7
Journal	Respirology
Volume	15
Issue number	7
DOIs	https://doi.org/10.1111/j.1440-1843.2010.01814.x
State	Published - Oct 2010
Externally published	Yes

Keywords

Streptococcus pneumoniae
Toll-like receptor
infectious disease
innate immunity
pattern recognition receptor

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Access to Document

10.1111/j.1440-1843.2010.01814.x

Cite this

@article{d16e5df5fabe49d3861e267a7f4a6cc6,

title = "Pneumococci: Immunology of the innate host response",

abstract = "Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.",

keywords = "Streptococcus pneumoniae, Toll-like receptor, infectious disease, innate immunity, pattern recognition receptor",

author = "Paterson, {Gavin K.} and Orihuela, {Carlos J.}",

year = "2010",

month = oct,

doi = "10.1111/j.1440-1843.2010.01814.x",

language = "English (US)",

volume = "15",

pages = "1057--1063",

journal = "Respirology",

issn = "1323-7799",

publisher = "Wiley-Blackwell",

number = "7",

}

TY - JOUR

T1 - Pneumococci

T2 - Immunology of the innate host response

AU - Paterson, Gavin K.

AU - Orihuela, Carlos J.

PY - 2010/10

Y1 - 2010/10

N2 - Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

AB - Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

KW - Streptococcus pneumoniae

KW - Toll-like receptor

KW - infectious disease

KW - innate immunity

KW - pattern recognition receptor

UR - http://www.scopus.com/inward/record.url?scp=77957253638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957253638&partnerID=8YFLogxK

U2 - 10.1111/j.1440-1843.2010.01814.x

DO - 10.1111/j.1440-1843.2010.01814.x

M3 - Review article

C2 - 20646240

AN - SCOPUS:77957253638

VL - 15

SP - 1057

EP - 1063

JO - Respirology

JF - Respirology

SN - 1323-7799

IS - 7

ER -

Pneumococci: Immunology of the innate host response

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this