Platelet activating factor and lyso-phosphatidylcholines from strawberry

Mary Calligerou, Athanassia Siafaka-Kapadai, Dia Galanopoulou, Suzan T. Weintraub, Mary Mavri-Vavayanni

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Lipids from strawberry fruits, leaves, achenes and pollen were separated into classes by TLC, purified by HPLC and tested for biological activity. A lipid fraction from fruits with the same chromatographic behaviour as authentic platelet activating factor (PAF) showed identical biological activity, namely, dose-dependent aggregation of washed rabbit platelets, inhibition of aggregation by CV 3988, platelet desensitization to PAF and vice versa, and loss of activity by alkaline hydrolysis and recovery of activity by reacetylation. The presence of PAF was confirmed by FAB mass spectrometry. Lyso-phosphatidylcholines, including lyso-PAF, were also found in all the plant parts tested.

Original languageEnglish (US)
Pages (from-to)89-92
Number of pages4
JournalPhytochemistry
Volume41
Issue number1
DOIs
StatePublished - Jan 1 1996
Externally publishedYes

Keywords

  • Ether lipids
  • Fragaria ananassa
  • Lyso-PAF
  • Phospholipids
  • Platelet activating factor (PAF)
  • Rosaceae
  • Strawberry

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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