Plasma volume in erythremic states

M. L. Nusynowitz, R. Blumhardt, J. Volpe

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Direct determinations by radioiodinated human serum albumin (RISA) of plasma volume were made in normals, patients with uncomplicated polycythemia vera, and in patients with erythremia associated with chronic lung disease. The results show a moderately severe contraction of plasma volume in both erythremic states, evidently a compensatory consequence of red cell volume expansion. The hematocrit, reflecting both red cell and plasma volumes, may therefore be misleading as to the status of the erythremic condition, and therapeutic maneuvers and responses thereto should be determined on the basis of repeated direct measurements of the red cell volume in erythremia.

Original languageEnglish (US)
Pages (from-to)31-34
Number of pages4
JournalAmerican Journal of the Medical Sciences
Issue number1
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • Medicine(all)


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