Pithomyces species (Montagnulaceae) from clinical specimens: Identification and antifungal susceptibility profiles

Keith Cássia Da Cunha, Deanna A. Sutton, Josepa Gené, Josep Cano, Javier Capilla, Hugo Madrid, Cony Decock, Nathan P. Wiederhold, Josep Guarro

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The fungal genus Pithomyces comprises numerous dematiaceous saprobic species commonly found on dead leaves and stems of a great variety of plants. Occasionally, they have been recovered from clinical specimens. We morphologically and molecularly (rDNA sequences) investigated a set of 42 isolates tentatively identified as Pithomyces recovered from clinical specimens in the United States. The predominant species were P. chartarum and P. sacchari (33.3% each), followed by Pithomyces sp. I (28.6%) and P. maydicus (4.8%). Most of the isolates were obtained from samples of superficial tissue (50%), the respiratory tract (21.4%), and the nasal region (19%). In general, these fungi were highly susceptible in vitro to the eight antifungal agents tested.

Original languageEnglish (US)
Pages (from-to)748-757
Number of pages10
JournalMedical mycology
Issue number7
StatePublished - Jul 22 2014


  • DNA analysis
  • Pithomyces
  • antifungal susceptibility
  • clinical specimens
  • morphological identification

ASJC Scopus subject areas

  • Infectious Diseases


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