Pineal-induced ovarian atrophy in rats treated neonatally with testosterone

Russel J. Reiter, Peter H. Rubin, John R. Richert

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Blinding 2 or 3 day old rats decreased uterine weights when animals were killed at 75 days of age; the effect of blinding was counteracted by pinealectomy. TP-treatment at 3 days of age reduced ovarian, but not uterine, size at 75 days of age. This decrease was not prevented by pinealectomy. The combination of blinding and TP-treatment caused marked reductions in the size of both the ovaries and uteri; if these rats were pinealectomized the ovaries and uteri returned to the levels of similar organs in TP-treated animals.

Original languageEnglish (US)
Pages (from-to)299-305
Number of pages7
JournalLife Sciences
Issue number5
StatePublished - Mar 1 1968
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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