Pineal-induced ovarian atrophy in rats treated neonatally with testosterone

Russel J Reiter, Peter H. Rubin, John R. Richert

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Blinding 2 or 3 day old rats decreased uterine weights when animals were killed at 75 days of age; the effect of blinding was counteracted by pinealectomy. TP-treatment at 3 days of age reduced ovarian, but not uterine, size at 75 days of age. This decrease was not prevented by pinealectomy. The combination of blinding and TP-treatment caused marked reductions in the size of both the ovaries and uteri; if these rats were pinealectomized the ovaries and uteri returned to the levels of similar organs in TP-treated animals.

Original languageEnglish (US)
Pages (from-to)299-305
Number of pages7
JournalLife Sciences
Volume7
Issue number5
StatePublished - Mar 1 1968
Externally publishedYes

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Uterus
Atrophy
Testosterone
Rats
Ovary
Animals
Weights and Measures

ASJC Scopus subject areas

  • Pharmacology

Cite this

Pineal-induced ovarian atrophy in rats treated neonatally with testosterone. / Reiter, Russel J; Rubin, Peter H.; Richert, John R.

In: Life Sciences, Vol. 7, No. 5, 01.03.1968, p. 299-305.

Research output: Contribution to journalArticle

Reiter, Russel J ; Rubin, Peter H. ; Richert, John R. / Pineal-induced ovarian atrophy in rats treated neonatally with testosterone. In: Life Sciences. 1968 ; Vol. 7, No. 5. pp. 299-305.
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