Abstract
Blinding 2 or 3 day old rats decreased uterine weights when animals were killed at 75 days of age; the effect of blinding was counteracted by pinealectomy. TP-treatment at 3 days of age reduced ovarian, but not uterine, size at 75 days of age. This decrease was not prevented by pinealectomy. The combination of blinding and TP-treatment caused marked reductions in the size of both the ovaries and uteri; if these rats were pinealectomized the ovaries and uteri returned to the levels of similar organs in TP-treated animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 299-305 |
| Number of pages | 7 |
| Journal | Life Sciences |
| Volume | 7 |
| Issue number | 5 |
| State | Published - Mar 1 1968 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pharmacology
Cite this
Pineal-induced ovarian atrophy in rats treated neonatally with testosterone. / Reiter, Russel J; Rubin, Peter H.; Richert, John R.
In: Life Sciences, Vol. 7, No. 5, 01.03.1968, p. 299-305.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pineal-induced ovarian atrophy in rats treated neonatally with testosterone
AU - Reiter, Russel J
AU - Rubin, Peter H.
AU - Richert, John R.
PY - 1968/3/1
Y1 - 1968/3/1
N2 - Blinding 2 or 3 day old rats decreased uterine weights when animals were killed at 75 days of age; the effect of blinding was counteracted by pinealectomy. TP-treatment at 3 days of age reduced ovarian, but not uterine, size at 75 days of age. This decrease was not prevented by pinealectomy. The combination of blinding and TP-treatment caused marked reductions in the size of both the ovaries and uteri; if these rats were pinealectomized the ovaries and uteri returned to the levels of similar organs in TP-treated animals.
AB - Blinding 2 or 3 day old rats decreased uterine weights when animals were killed at 75 days of age; the effect of blinding was counteracted by pinealectomy. TP-treatment at 3 days of age reduced ovarian, but not uterine, size at 75 days of age. This decrease was not prevented by pinealectomy. The combination of blinding and TP-treatment caused marked reductions in the size of both the ovaries and uteri; if these rats were pinealectomized the ovaries and uteri returned to the levels of similar organs in TP-treated animals.
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UR - http://www.scopus.com/inward/citedby.url?scp=0014266933&partnerID=8YFLogxK
M3 - Article
VL - 7
SP - 299
EP - 305
JO - Life Sciences
JF - Life Sciences
SN - 0024-3205
IS - 5
ER -