Abstract
On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.
Original language | English (US) |
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Pages (from-to) | 3051-3057 |
Number of pages | 7 |
Journal | Small |
Volume | 9 |
Issue number | 18 |
DOIs | |
State | Published - Sep 23 2013 |
Externally published | Yes |
Keywords
- biopolymers
- drug delivery
- electrospinning
- nanoparticles
- photoswitching
ASJC Scopus subject areas
- Biotechnology
- General Chemistry
- Biomaterials
- General Materials Science
- Engineering (miscellaneous)