Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster

M. K. Vaughan; G. C. Brainard; R. J. Reiter

doi:10.1016/0024-3205(85)90327-3

Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster

M. K. Vaughan, G. C. Brainard, R. J. Reiter

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Adult male Syrian hamsters were exposed daily for 12 weeks to 11 h/day of cool white fluorescent light (350 ± 50 μW/cm²) followed by an additional 3 h of near ultraviolet (339-317 nm), blue (435-500 nm), green (515-550 nm), yellow (558-636 nm) or red (653-668 nm) light at an irradiance of 0.2 μW/cm² or to total darkness. Animals exposed to the wavelengths between 558-668 nm (yellow or red half peak bandwidths) or those receiving a total of 13 h of darkness/day had suppressed circulating levels of thyroxine (T₄), a depressed free T₄ index (FT₄I) and a higher T₃/T₄ ratio compared to animals receiving a total of 14 h of white light (350 ± 50 μW/cm²). These results suggest that specific wavelengths of light can affect the neuroendocrine-thyroid axis.

Original language	English (US)
Pages (from-to)	2183-2188
Number of pages	6
Journal	Life Sciences
Volume	36
Issue number	23
DOIs	https://doi.org/10.1016/0024-3205(85)90327-3
State	Published - Jun 10 1985

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
General Biochemistry, Genetics and Molecular Biology

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@article{d9aec31bf80e49789e53d5d257b03a69,

title = "Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster",

abstract = "Adult male Syrian hamsters were exposed daily for 12 weeks to 11 h/day of cool white fluorescent light (350 ± 50 μW/cm2) followed by an additional 3 h of near ultraviolet (339-317 nm), blue (435-500 nm), green (515-550 nm), yellow (558-636 nm) or red (653-668 nm) light at an irradiance of 0.2 μW/cm2 or to total darkness. Animals exposed to the wavelengths between 558-668 nm (yellow or red half peak bandwidths) or those receiving a total of 13 h of darkness/day had suppressed circulating levels of thyroxine (T4), a depressed free T4 index (FT4I) and a higher T3/T4 ratio compared to animals receiving a total of 14 h of white light (350 ± 50 μW/cm2). These results suggest that specific wavelengths of light can affect the neuroendocrine-thyroid axis.",

author = "Vaughan, {M. K.} and Brainard, {G. C.} and Reiter, {R. J.}",

note = "Funding Information: This work was supported by NSF grant #PCM8003441. The authors w~sh to thank the Durotest Corporation for the donation of the fluorescent light used ~n the present study.",

year = "1985",

month = jun,

day = "10",

doi = "10.1016/0024-3205(85)90327-3",

language = "English (US)",

volume = "36",

pages = "2183--2188",

journal = "Life Sciences",

issn = "0024-3205",

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T1 - Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster

AU - Vaughan, M. K.

AU - Brainard, G. C.

AU - Reiter, R. J.

N1 - Funding Information: This work was supported by NSF grant #PCM8003441. The authors w~sh to thank the Durotest Corporation for the donation of the fluorescent light used ~n the present study.

PY - 1985/6/10

Y1 - 1985/6/10

N2 - Adult male Syrian hamsters were exposed daily for 12 weeks to 11 h/day of cool white fluorescent light (350 ± 50 μW/cm2) followed by an additional 3 h of near ultraviolet (339-317 nm), blue (435-500 nm), green (515-550 nm), yellow (558-636 nm) or red (653-668 nm) light at an irradiance of 0.2 μW/cm2 or to total darkness. Animals exposed to the wavelengths between 558-668 nm (yellow or red half peak bandwidths) or those receiving a total of 13 h of darkness/day had suppressed circulating levels of thyroxine (T4), a depressed free T4 index (FT4I) and a higher T3/T4 ratio compared to animals receiving a total of 14 h of white light (350 ± 50 μW/cm2). These results suggest that specific wavelengths of light can affect the neuroendocrine-thyroid axis.

AB - Adult male Syrian hamsters were exposed daily for 12 weeks to 11 h/day of cool white fluorescent light (350 ± 50 μW/cm2) followed by an additional 3 h of near ultraviolet (339-317 nm), blue (435-500 nm), green (515-550 nm), yellow (558-636 nm) or red (653-668 nm) light at an irradiance of 0.2 μW/cm2 or to total darkness. Animals exposed to the wavelengths between 558-668 nm (yellow or red half peak bandwidths) or those receiving a total of 13 h of darkness/day had suppressed circulating levels of thyroxine (T4), a depressed free T4 index (FT4I) and a higher T3/T4 ratio compared to animals receiving a total of 14 h of white light (350 ± 50 μW/cm2). These results suggest that specific wavelengths of light can affect the neuroendocrine-thyroid axis.

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ER -

Photoperiodic and light spectral conditions which inhibit circulating concentrations of thyroxine in the male hamster

Abstract

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