Photoacoustic emission from fluorescent nanodiamonds enhanced with gold nanoparticles

Bailin Zhang; Chia Yi Fang; Cheng Chun Chang; Ralph Peterson; Saher Maswadi; Randolph D. Glickman; Huan Cheng Chang; Jing Yong Ye

doi:10.1364/BOE.3.001662

Photoacoustic emission from fluorescent nanodiamonds enhanced with gold nanoparticles

Bailin Zhang, Chia Yi Fang, Cheng Chun Chang, Ralph Peterson, Saher Maswadi, Randolph D. Glickman, Huan Cheng Chang, Jing Yong Ye

Ophthalmology

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Fluorescent nanodiamonds (FNDs) have drawn much attention in recent years for biomedical imaging applications due to their desired physical properties including excellent photostability, high biocompatibility, extended far-red fluorescence emission, and ease of surface functionalization. Here we explore a new feature of FNDs, i.e. their photoacoustic emission capability, which may lead to potential applications of using FNDs as a dual imaging contrast agent for combined fluorescence and photoacoustic imaging modalities. We observed significant enhancement of photoacoustic emission from FNDs when they were conjugated with gold nanoparticles (GNPs).

Original language	English (US)
Pages (from-to)	1662-1669
Number of pages	8
Journal	Biomedical Optics Express
Volume	3
Issue number	7
DOIs	https://doi.org/10.1364/BOE.3.001662
State	Published - Jul 1 2012

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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title = "Photoacoustic emission from fluorescent nanodiamonds enhanced with gold nanoparticles",

abstract = "Fluorescent nanodiamonds (FNDs) have drawn much attention in recent years for biomedical imaging applications due to their desired physical properties including excellent photostability, high biocompatibility, extended far-red fluorescence emission, and ease of surface functionalization. Here we explore a new feature of FNDs, i.e. their photoacoustic emission capability, which may lead to potential applications of using FNDs as a dual imaging contrast agent for combined fluorescence and photoacoustic imaging modalities. We observed significant enhancement of photoacoustic emission from FNDs when they were conjugated with gold nanoparticles (GNPs).",

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AU - Zhang, Bailin

AU - Fang, Chia Yi

AU - Chang, Cheng Chun

AU - Peterson, Ralph

AU - Maswadi, Saher

AU - Glickman, Randolph D.

AU - Chang, Huan Cheng

AU - Ye, Jing Yong

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AB - Fluorescent nanodiamonds (FNDs) have drawn much attention in recent years for biomedical imaging applications due to their desired physical properties including excellent photostability, high biocompatibility, extended far-red fluorescence emission, and ease of surface functionalization. Here we explore a new feature of FNDs, i.e. their photoacoustic emission capability, which may lead to potential applications of using FNDs as a dual imaging contrast agent for combined fluorescence and photoacoustic imaging modalities. We observed significant enhancement of photoacoustic emission from FNDs when they were conjugated with gold nanoparticles (GNPs).

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