Photoacoustic emission from fluorescent nanodiamonds enhanced with gold nanoparticles

Bailin Zhang, Chia Yi Fang, Cheng Chun Chang, Ralph Peterson, Saher Maswadi, Randolph D. Glickman, Huan Cheng Chang, Jing Yong Ye

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Fluorescent nanodiamonds (FNDs) have drawn much attention in recent years for biomedical imaging applications due to their desired physical properties including excellent photostability, high biocompatibility, extended far-red fluorescence emission, and ease of surface functionalization. Here we explore a new feature of FNDs, i.e. their photoacoustic emission capability, which may lead to potential applications of using FNDs as a dual imaging contrast agent for combined fluorescence and photoacoustic imaging modalities. We observed significant enhancement of photoacoustic emission from FNDs when they were conjugated with gold nanoparticles (GNPs).

Original languageEnglish (US)
Pages (from-to)1662-1669
Number of pages8
JournalBiomedical Optics Express
Volume3
Issue number7
DOIs
StatePublished - Jul 1 2012

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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