Phialosimplex, a new anamorphic genus associated with infections in dogs and having phylogenetic affinity to the Trichocomaceae

Lynne Sigler, Deanna A. Sutton, Connie Fe C. Gibas, Richard C. Summerbell, Rhonda K. Noel, Peter C. Iwen

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Anamorphic members of the ascomycete family Trichocomaceae including Aspergillus, Penicillium, Paecilomyces, Geosmithia and Sagenomella have been reported from infections in canines. Six clinical isolates (five associated with infections in canines and one from a human source) demonstrated simple phialides producing conidia in long chains and were investigated for their potential relationship to Sagenomella chlamydospora, a known agent of canine disseminated mycosis. Phylogenetic analyses of internal transcribed spacer (ITS) and small subunit (SSU) region sequences revealed that all of the canine-associated isolates were distinct from Sagenomella species. The new anamorphic genus and species Phialosimplex caninus is described to accommodate the clinical isolates. Sagenomella chlamydospora and Sagenomella sclerotialis are transferred to the new genus as Phialosimplex chlamydosporus comb. nov. and Phialosimplex sclerotialis comb. nov.

Original languageEnglish (US)
Pages (from-to)335-345
Number of pages11
JournalMedical mycology
Volume48
Issue number2
DOIs
StatePublished - 2010

Keywords

  • Canine fungal infection
  • Monocillium indicum
  • Phialosimplex caninus
  • Sagenomella chlamydospora
  • Trichocomaceaer

ASJC Scopus subject areas

  • Infectious Diseases

Fingerprint Dive into the research topics of 'Phialosimplex, a new anamorphic genus associated with infections in dogs and having phylogenetic affinity to the Trichocomaceae'. Together they form a unique fingerprint.

Cite this