Medidas farmacológicas para la prevencin de la neumonía asociada a la ventilación mecánica

Marta Ulldemolins; Marcos I. Restrepo; Jordi Rello

doi:10.1016/j.medcli.2009.10.012

Medidas farmacológicas para la prevencin de la neumonía asociada a la ventilación mecánica

Translated title of the contribution: Pharmacologic measures for the prevention of mechanical ventilation-associated pneumonia

Marta Ulldemolins, Marcos I. Restrepo, Jordi Rello

Medicine

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.

Translated title of the contribution	Pharmacologic measures for the prevention of mechanical ventilation-associated pneumonia
Original language	Spanish
Pages (from-to)	21-25
Number of pages	5
Journal	Medicina Clinica
Volume	136
Issue number	1
DOIs	https://doi.org/10.1016/j.medcli.2009.10.012
State	Published - Jan 15 2011

Keywords

Antibiotics
Infection prevention
Intensive care unit
Mechanical ventilation
Nosocomial infection

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/j.medcli.2009.10.012

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Cite this

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title = "Medidas farmacol{\'o}gicas para la prevencin de la neumon{\'i}a asociada a la ventilaci{\'o}n mec{\'a}nica",

abstract = "Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.",

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