Medidas farmacológicas para la prevencin de la neumonía asociada a la ventilación mecánica

Translated title of the contribution: Pharmacologic measures for the prevention of mechanical ventilation-associated pneumonia

Marta Ulldemolins, Marcos I. Restrepo, Jordi Rello

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.

Translated title of the contributionPharmacologic measures for the prevention of mechanical ventilation-associated pneumonia
Original languageSpanish
Pages (from-to)21-25
Number of pages5
JournalMedicina Clinica
Volume136
Issue number1
DOIs
StatePublished - Jan 15 2011

Keywords

  • Antibiotics
  • Infection prevention
  • Intensive care unit
  • Mechanical ventilation
  • Nosocomial infection

ASJC Scopus subject areas

  • Medicine(all)

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