Abstract
Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.
| Original language | Spanish |
|---|---|
| Pages (from-to) | 21-25 |
| Number of pages | 5 |
| Journal | Medicina Clinica |
| Volume | 136 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 15 2011 |
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Keywords
- Antibiotics
- Infection prevention
- Intensive care unit
- Mechanical ventilation
- Nosocomial infection
ASJC Scopus subject areas
- Medicine(all)
Cite this
Medidas farmacológicas para la prevencin de la neumonía asociada a la ventilación mecánica. / Ulldemolins, Marta; Restrepo, Marcos; Rello, Jordi.
In: Medicina Clinica, Vol. 136, No. 1, 15.01.2011, p. 21-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Medidas farmacológicas para la prevencin de la neumonía asociada a la ventilación mecánica
AU - Ulldemolins, Marta
AU - Restrepo, Marcos
AU - Rello, Jordi
PY - 2011/1/15
Y1 - 2011/1/15
N2 - Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.
AB - Ventilator associated pneumonia is the principal infectious complication in the Intensive Care Unit (ICU), and represents the main infectious cause of morbidity and mortality. Its diagnosis and management is complex. Consequently, its prevention becomes a cornerstone in daily clinical practice. Daily interruption of sedation, oral and digestive decontamination, prophylactic administration of systemic and/or inhaled antibiotics, glycemic control, stress ulcer prophylaxis, transfusion policy and timing and adequacy of antibiotic treatment are the main suggested pharmacologic interventions. The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice.
KW - Antibiotics
KW - Infection prevention
KW - Intensive care unit
KW - Mechanical ventilation
KW - Nosocomial infection
UR - http://www.scopus.com/inward/record.url?scp=78751577583&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78751577583&partnerID=8YFLogxK
U2 - 10.1016/j.medcli.2009.10.012
DO - 10.1016/j.medcli.2009.10.012
M3 - Article
C2 - 20022067
AN - SCOPUS:78751577583
VL - 136
SP - 21
EP - 25
JO - Medicina Clinica
JF - Medicina Clinica
SN - 0025-7753
IS - 1
ER -