Persistent pulmonary infection with an azole-resistant Coccidioides species

John D. Kriesel; Deanna A. Sutton; Susan Schulman; Annette W. Fothergill; Michael G. Rinaldi

doi:10.1080/13693780802140923

Persistent pulmonary infection with an azole-resistant Coccidioides species

John D. Kriesel, Deanna A. Sutton, Susan Schulman, Annette W. Fothergill, Michael G. Rinaldi

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We report a case of a life-threatening, recurrent, and azole-resistant pulmonary coccidioidomycosis in a patient receiving long-term fluconazole therapy for a history of coccidioidal meningitis. Since this diagnosis, the patient has received weekly amphotericin B for more than four years and remains in remission with a stable serum Coccidioides complement fixation antibody titer.

Original language	English (US)
Pages (from-to)	607-610
Number of pages	4
Journal	Medical mycology
Volume	46
Issue number	6
DOIs	https://doi.org/10.1080/13693780802140923
State	Published - 2008

Keywords

Amphotericin B
Azole resistance
Coccidioides
Coccidioidomycosis
Drug resistance

ASJC Scopus subject areas

Infectious Diseases

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abstract = "We report a case of a life-threatening, recurrent, and azole-resistant pulmonary coccidioidomycosis in a patient receiving long-term fluconazole therapy for a history of coccidioidal meningitis. Since this diagnosis, the patient has received weekly amphotericin B for more than four years and remains in remission with a stable serum Coccidioides complement fixation antibody titer.",

keywords = "Amphotericin B, Azole resistance, Coccidioides, Coccidioidomycosis, Drug resistance",

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AU - Rinaldi, Michael G.

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AB - We report a case of a life-threatening, recurrent, and azole-resistant pulmonary coccidioidomycosis in a patient receiving long-term fluconazole therapy for a history of coccidioidal meningitis. Since this diagnosis, the patient has received weekly amphotericin B for more than four years and remains in remission with a stable serum Coccidioides complement fixation antibody titer.

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