Peripartum cardiomyopathy: a review

Corina Iorgoveanu, Ahmed Zaghloul, Mahi Ashwath

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Peripartum cardiomyopathy is a form of idiopathic systolic heart failure which occurs during the end of pregnancy or the early post-partum in the absence of an identifiable etiology. The exact pathogenesis remains unknown, and the incidence is higher in African ancestry, multiparous and hypertensive women, or older maternal age. Delay in diagnosis is common, mainly because symptoms of heart failure mimic those of normal pregnancy. Echocardiography showing decreased myocardial function is at the center of the diagnosis. Management relies on the general guidelines of management of other forms of non-ischemic cardiomyopathy; however, special attention should be paid when choosing medications to ensure fetal safety. Outcomes can be variable and can range from complete recovery to persistent heart failure requiring transplant or even death. High rates of relapse with subsequent pregnancies can occur, especially with incomplete myocardial recovery. Additional research about the etiology, experimental drugs, prognosis, and duration of treatment after recovery are needed.

Original languageEnglish (US)
Pages (from-to)1287-1296
Number of pages10
JournalHeart Failure Reviews
Issue number6
StatePublished - Nov 2021
Externally publishedYes


  • Heart failure
  • Peripartum cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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