TY - JOUR
T1 - Periodontitis is a factor associated with dyslipidemia
AU - Gomes-Filho, Isaac Suzart
AU - Oliveira, Michelle Teixeira
AU - Cruz, Simone Seixas da
AU - Cerqueira, Eneida de Moraes Marcílio
AU - Trindade, Soraya Castro
AU - Vieira, Graciete Oliveira
AU - Couto Souza, Paulo Henrique
AU - Adan, Luis Fernando Fernandes
AU - Hintz, Alexandre Marcelo
AU - Passos-Soares, Johelle de Santana
AU - Scannapieco, Frank Andrew
AU - Loomer, Peter Michael
AU - Seymour, Gregory John
AU - Figueiredo, Ana Claudia Morais Godoy
N1 - Publisher Copyright:
© 2021 Wiley Periodicals LLC
PY - 2022/4
Y1 - 2022/4
N2 - Objective: To investigate the association between the severity of periodontitis (exposure) and dyslipidemia (outcome). Methods: This was a cross-sectional study of users of public health services. Periodontitis was defined using the Center for Disease Prevention and Control and the American Academy of Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis was based on the Guidelines of total cardiovascular risk of the World Health Organization. Weight, height, waist circumference, and blood pressure were measured, and socioeconomic–demographic, lifestyle behavior factors, general and oral health conditions of the participants were collected. Hierarchical and logistic regression analyzes were used to determine the association between the exposures and the outcome. Odds Ratios, unadjusted and adjusted, and 95% confidence intervals were estimated. Results: Of 1,011 individuals examined, 75.17% had dyslipidemia, and 84.17% had periodontitis, 0.2% with mild, 48.56% moderate, and 35.41% severe disease. The association between periodontitis and dyslipidemia was maintained through hierarchical analysis and in the multiple regression modeling, showing that the occurrences of dyslipidemia in the group with periodontitis, and its moderate and severe levels, were, respectively, 14%, 30%, and 16% higher compared with those without periodontitis. Conclusions: The results showed a positive association between moderate and severe periodontitis and dyslipidemia.
AB - Objective: To investigate the association between the severity of periodontitis (exposure) and dyslipidemia (outcome). Methods: This was a cross-sectional study of users of public health services. Periodontitis was defined using the Center for Disease Prevention and Control and the American Academy of Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis was based on the Guidelines of total cardiovascular risk of the World Health Organization. Weight, height, waist circumference, and blood pressure were measured, and socioeconomic–demographic, lifestyle behavior factors, general and oral health conditions of the participants were collected. Hierarchical and logistic regression analyzes were used to determine the association between the exposures and the outcome. Odds Ratios, unadjusted and adjusted, and 95% confidence intervals were estimated. Results: Of 1,011 individuals examined, 75.17% had dyslipidemia, and 84.17% had periodontitis, 0.2% with mild, 48.56% moderate, and 35.41% severe disease. The association between periodontitis and dyslipidemia was maintained through hierarchical analysis and in the multiple regression modeling, showing that the occurrences of dyslipidemia in the group with periodontitis, and its moderate and severe levels, were, respectively, 14%, 30%, and 16% higher compared with those without periodontitis. Conclusions: The results showed a positive association between moderate and severe periodontitis and dyslipidemia.
KW - dyslipidemia
KW - epidemiology
KW - periodontal medicine
KW - periodontitis
KW - public health
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U2 - 10.1111/odi.13779
DO - 10.1111/odi.13779
M3 - Article
C2 - 33486821
AN - SCOPUS:85101018978
SN - 1354-523X
VL - 28
SP - 813
EP - 823
JO - Oral Diseases
JF - Oral Diseases
IS - 3
ER -