Periodontitis is a factor associated with dyslipidemia

Isaac Suzart Gomes-Filho, Michelle Teixeira Oliveira, Simone Seixas da Cruz, Eneida de Moraes Marcílio Cerqueira, Soraya Castro Trindade, Graciete Oliveira Vieira, Paulo Henrique Couto Souza, Luis Fernando Fernandes Adan, Alexandre Marcelo Hintz, Johelle de Santana Passos-Soares, Frank Andrew Scannapieco, Peter Michael Loomer, Gregory John Seymour, Ana Claudia Morais Godoy Figueiredo

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Objective: To investigate the association between the severity of periodontitis (exposure) and dyslipidemia (outcome). Methods: This was a cross-sectional study of users of public health services. Periodontitis was defined using the Center for Disease Prevention and Control and the American Academy of Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis was based on the Guidelines of total cardiovascular risk of the World Health Organization. Weight, height, waist circumference, and blood pressure were measured, and socioeconomic–demographic, lifestyle behavior factors, general and oral health conditions of the participants were collected. Hierarchical and logistic regression analyzes were used to determine the association between the exposures and the outcome. Odds Ratios, unadjusted and adjusted, and 95% confidence intervals were estimated. Results: Of 1,011 individuals examined, 75.17% had dyslipidemia, and 84.17% had periodontitis, 0.2% with mild, 48.56% moderate, and 35.41% severe disease. The association between periodontitis and dyslipidemia was maintained through hierarchical analysis and in the multiple regression modeling, showing that the occurrences of dyslipidemia in the group with periodontitis, and its moderate and severe levels, were, respectively, 14%, 30%, and 16% higher compared with those without periodontitis. Conclusions: The results showed a positive association between moderate and severe periodontitis and dyslipidemia.

Original languageEnglish (US)
Pages (from-to)813-823
Number of pages11
JournalOral Diseases
Issue number3
StatePublished - Apr 2022


  • dyslipidemia
  • epidemiology
  • periodontal medicine
  • periodontitis
  • public health

ASJC Scopus subject areas

  • General Dentistry
  • Otorhinolaryngology


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