Perfusion thallium imaging of type I diabetes patients with end stage renal disease: Comparison of oral and intravenous dipyridamole administration

Robert J. Boudreau, John T. Strony, Rene P. DuCret, Christopher C. Kuni, Yang Wang, Robert F. Wilson, Jeffrey S. Schwartz, Wilfrido R. Castaneda-Zuniga

Research output: Contribution to journalReview article

77 Scopus citations

Abstract

Eighty patients with type I diabetes and end stage renal disease were prospectively evaluated for coronary artery disease with dipyridamole-thallium-201 scintigraphy and quantitative coronary angiography. Forty patients received dipyridamole orally, and 40 received it intravenously. The prevalence of coronary artery disease was 53%. There were no significant differences in the accuracy of the two dipyridamole tests (sensitivity = 85%, specificity = 85%, accuracy = 85% for the oral group; sensitivity = 86%, specificity = 72%, accuracy = 79% for the intravenous group). Combining the 80 patients into a single group gave a sensitivity of 86%, a specificity of 79%, and an accuracy of 83% for the detection of coronary disease. Although the accuracy of this test in this patient population was similar to that previously reported for other groups, the prevalence of disease was high and resulted in a low predictive value of a negative test (83%).

Original languageEnglish (US)
Pages (from-to)103-105
Number of pages3
JournalRadiology
Volume175
Issue number1
DOIs
StatePublished - Apr 1990

Keywords

  • Coronary vessels, diseases, 54.76
  • Coronary vessels, radionuclide studies, 54.1299
  • Diabetes mellitus, complications, 96.724
  • Dipyridamole
  • Heart, effects of drugs on
  • Kidney, failure, 81.79
  • Thallium, radioactive

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Boudreau, R. J., Strony, J. T., DuCret, R. P., Kuni, C. C., Wang, Y., Wilson, R. F., Schwartz, J. S., & Castaneda-Zuniga, W. R. (1990). Perfusion thallium imaging of type I diabetes patients with end stage renal disease: Comparison of oral and intravenous dipyridamole administration. Radiology, 175(1), 103-105. https://doi.org/10.1148/radiology.175.1.2315467