Percutaneous transluminal angioplasty of the aorta. Light and electron microscopic observations in normal and atherosclerotic rabbits

C. L. Zollikofer, J. Chain, E. Salomonowitz, W. Runge, W. F. Bruehlmann, W. R. Castaneda-Zuniga, K. Amplatz

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Histological changes which developed after percutaneous transluminal angioplasty in normal and atherosclerotic rabbit aortas were correlated with balloon size and inflation time. In normal rabbits, progressive changes were observed in the intima and media with increasing balloon size and inflation time. The atherosclerotic aortas exhibited unpredictable fragility, with limited correlation between histological changes, balloon size, and inflation time, attributable mainly to the distribution and thickness of plaques. In atherosclerotic vessels, the mechanism of angioplasty consisted of plaque dehiscence and fracture, followed by overstretching of the plaque-free wall segments. No plaque compression was observed.

Original languageEnglish (US)
Pages (from-to)355-363
Number of pages9
JournalRadiology
Volume151
Issue number2
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Percutaneous transluminal angioplasty of the aorta. Light and electron microscopic observations in normal and atherosclerotic rabbits'. Together they form a unique fingerprint.

Cite this