Percutaneous Therapy for Renal Artery Fibromuscular Dysplasia

Scott M. Surowiec, Nayan Sivamurthy, Jeffrey M. Rhodes, David E. Lee, David L. Waldman, Richard M. Green, Mark G. Davies

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Fibromuscular dysplasia (FMD) accounts for 10% of cases of renal artery stenosis. This study evaluates the anatomic and functional outcomes of endovascular therapy for symptomatic renal artery FMD at an academic medical center. A retrospective analysis of records from patients who underwent percutaneous transluminal renal artery angioplasty (PTRA) found 14 patients (all female) who underwent 19 interventions on 18 renal artery segments. Significant cardiovascular comorbidities were few in this patient population. The PTRA technical success rate was 95%. There were no periprocedural mortalities. Primary patency rates were 81%, 69%, 69%, and 69% at 2, 4, 6, and 8 years. Assisted primary patency rates were 87%, 87%, 87%, and 87% at 2, 4, 6, and 8 years. The restenosis rate was 25% at 8 years. Clinical benefit (improved or cured hypertension) was seen in 79% of patients overall; 65% of patients maintained this benefit at 8 years by life-table analysis. Percutaneous endovascular intervention for clinically symptomatic FMD of the renal arteries is technically successful, safe, and durable. Most patients demonstrate immediate clinical benefit and retain durable functional outcomes.

Original languageEnglish (US)
Pages (from-to)650-655
Number of pages6
JournalAnnals of Vascular Surgery
Volume17
Issue number6
DOIs
StatePublished - Nov 2003
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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    Surowiec, S. M., Sivamurthy, N., Rhodes, J. M., Lee, D. E., Waldman, D. L., Green, R. M., & Davies, M. G. (2003). Percutaneous Therapy for Renal Artery Fibromuscular Dysplasia. Annals of Vascular Surgery, 17(6), 650-655. https://doi.org/10.1007/s10016-003-0070-6