Peptide-functionalized protein-resistant adlayers on titanium surfaces: An approach for producing cell-selective biomaterial surfaces

M. Schuler, S. Tosatti, G. R. Owen, Z. Schwartz, M. Wieland, D. M. Brunette, B. D. Boyan, M. Textor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The response of osteoblast cells to smooth and rough Ti surfaces that were modified with different amounts of RGD-functionalized poly-L-lysine-g- poly(ethylene glycol) (PLL-g-PEG) adlayers were investigated. Investigations of cell attachment and adhesion indicated that osteoblasts adhere preferentially to rough compared to smooth surfaces. Strong correlations between the cell shape and cell differentiation were also suggested. The results indicated that cell motility is also affected by the density of surface-ligands.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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