Peptide coated vascular grafts: An in vivo study in sheep

A. Hill, C. Li, F. Tio, Y. Zheng, M. Imran

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The efficacy of P15 cell-binding peptide coated ePTFE grafts was compared to uncoated control ePTFE grafts. The efficacy was compared in terms of firstly, neo-intimal tissue in-growth at the arterial and venous ends of the graft and secondly, the coverage and the uniformity of endothelial cell resurfacing of the graft, and the patency of the arterial-venous (A-V) graft in sheep. The neointimal thickness and in-growth length of P15 coated grafts and uncoated grafts were measured by light microscopy. SEM study showed that P15 coated grafts had a more uniform endothelial cell coverage on the lumen of the graft compared to uncoated grafts.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)


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