Penicilloitins A and B, new antimicrobial fatty acid esters from a marine endophytic Penicillium species

Samar S A Mourshid; Jihan M. Badr; April L Risinger; Susan L Mooberry; Diaa T A Youssef

doi:10.1515/znc-2015-0242

Penicilloitins A and B, new antimicrobial fatty acid esters from a marine endophytic Penicillium species

Samar S A Mourshid, Jihan M. Badr, April L Risinger, Susan L Mooberry, Diaa T A Youssef

Pharmacology

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

Two new antimicrobial fatty acid esters, penicilloitins A and B (1 and 2), along with α-cyclopiazonic acid (3), tryptamine (4) and indole-3-carbaldehyde (5), were isolated from mycelial extracts and the culture broth of a marine endophytic Penicillium species and their structures established by spectroscopic techniques including 1D (¹H NMR and ¹³C NMR) and 2D NMR (COSY, multiplicity-edited HSQC, and HMBC) as well as HRESIMS. Of these compounds, 1, 3 and 4 displayed modest antimicrobial activity.

Original language	English (US)
Pages (from-to)	387-392
Number of pages	6
Journal	Zeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume	71
Issue number	11-12
DOIs	https://doi.org/10.1515/znc-2015-0242
State	Published - Nov 1 2016

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Keywords

antimicrobial
Didemnum
fatty acid esters
Penicillium

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Mourshid, S. S. A., Badr, J. M., Risinger, A. L., Mooberry, S. L., & Youssef, D. T. A. (2016). Penicilloitins A and B, new antimicrobial fatty acid esters from a marine endophytic Penicillium species. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 71(11-12), 387-392. https://doi.org/10.1515/znc-2015-0242

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10.1515/znc-2015-0242