Penicilloitins A and B, new antimicrobial fatty acid esters from a marine endophytic Penicillium species

Samar S.A. Mourshid, Jihan M. Badr, April L. Risinger, Susan L. Mooberry, Diaa T.A. Youssef

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Two new antimicrobial fatty acid esters, penicilloitins A and B (1 and 2), along with α-cyclopiazonic acid (3), tryptamine (4) and indole-3-carbaldehyde (5), were isolated from mycelial extracts and the culture broth of a marine endophytic Penicillium species and their structures established by spectroscopic techniques including 1D (1H NMR and 13C NMR) and 2D NMR (COSY, multiplicity-edited HSQC, and HMBC) as well as HRESIMS. Of these compounds, 1, 3 and 4 displayed modest antimicrobial activity.

Original languageEnglish (US)
Pages (from-to)387-392
Number of pages6
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume71
Issue number11-12
DOIs
StatePublished - Nov 1 2016

Keywords

  • Didemnum
  • Penicillium
  • antimicrobial
  • fatty acid esters

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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