Penetration difference of n-butyl 2-cyanoacrylate into the nidus in the embolisation of brain arteriovenous malformation

Dae Chul Suh, Jun Hyoung Kim, Moo Song Lee, Sangsoo Park, Sung Tae Kim, Choong Gon Choi, Ho Kyu Lee, Chang Jin Kim, Ho Young Song

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Prediction of nidal penetration of the glue is difficult in the embolisation of brain arteriovenous malformations (AVM). We evaluated penetration differences of glue-lipiodol mixtures with and without tungsten powder for embolisation of brain AVM. Fifty eight injections during embolisation of brain AVM in 15 patients were evaluated. Glue contained lipiodol only (N=25), or lipiodol and tungsten powder (N=33). Glue concentration ranged from 20 to 80%. Injection was done at the pedicle (N=41) or nidus (N=17). Degree of penetration was rated as good, fair, or poor according to penetrated glue amount in the nidus. Penetration difference was compared in each injection at the pedicle or nidus. When the glue mixtures were injected at the pedicle, the glue-lipiodol mixture (GLM) penetrated into the nidus in eight of 16 injections (50%) and the glue-lipiodol-tungsten mixtures (GLTM) in 23 of 25 (92%). When glue was injected at the nidus, GLM was confined to the nidus in nine of nine injections (100%) and GLTM in seven of eight (88%). Penetration into the vein was noted in two of 25 injections (8%) in GLM and six of 33 (18%) in GLTM. Penetration difference into the nidus between GLM and GLTM was statistically significant (p< 0.05) when the glue mixtures were injected at the pedicle. GLM and GLTM can be used effectively at the nidus. In contrast to GLM, GLTM can be used effectively at the pedicle. However, the risk of venous penetration seemed to be higher with GLTM than in GLM.

Original languageEnglish (US)
Pages (from-to)63-74
Number of pages12
JournalInterventional Neuroradiology
Volume4
Issue number1
DOIs
StatePublished - Mar 1998
Externally publishedYes

Keywords

  • Arteriovenous malformations
  • Embolic agents
  • Embolisation
  • Interventional materials

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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