Pedigree analysis by computer simulation

Jean W. MacCluer, John L. VandeBerg, Bruce Read, Oliver A. Ryder

Research output: Contribution to journalArticle

198 Scopus citations

Abstract

Computer simulation is a valuable tool in the genetic management of captive populations. It can be used to assess the extent of genetic variability in a colony, to predict the risk of future loss of variability, or to identify likely ancestral sources of traits of interest. “Gene dropping” is a simulation procedure in which hypothetical alleles are assigned to each colony founder, and a genotype is created for each descendant by Mendelian segregation of parental alleles. The gene dropping method is applied to analyses of four populations: (1) a colony of small South American marsupials, Monodelphis domestica; (2) Speke's gazelles, Gazella spekei; (3) Przewalski's horses, Equus przewalskii; and (4) American Standardbred horses.

Original languageEnglish (US)
Pages (from-to)147-160
Number of pages14
JournalZoo Biology
Volume5
Issue number2
DOIs
StatePublished - 1986
Externally publishedYes

    Fingerprint

Keywords

  • gene dropping
  • genetic management

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

MacCluer, J. W., VandeBerg, J. L., Read, B., & Ryder, O. A. (1986). Pedigree analysis by computer simulation. Zoo Biology, 5(2), 147-160. https://doi.org/10.1002/zoo.1430050209